PET-CT in Lymphoma Among the Eldery

PET-CT Imaging Findings and Metabolic Parameters in Elderly Patients With Lymphoma

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07259941

Enrollment

Registered

2025-12-02

Start date

2026-01-01

Completion date

2027-02-01

Last updated

2025-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly, Lymphoma, Metabolic Parameters, PET-CT

Keywords

PET-CT, Lymphoma, Elderly, metabolic parameters

Brief summary

This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.

Detailed description

This cross-sectional study involves both retrospective and prospective data collection from elderly lymphoma patients (aged 60 years or older) at the Nuclear Medicine Unit, South Egypt Cancer Institute. It evaluates the PET-CT imaging findings alongside metabolic parameters such as Standardized Uptake Value (SUV), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG). The study addresses diagnostic challenges in elderly patients due to atypical presentations and comorbidities and fills the gap of scarce local data in Egypt. Imaging analysis includes visual and semiquantitative assessment of lymphatic and extranodal lesions post-injection of 18F-FDG, assessing tumor metabolic activity to provide prognostic insights. Data analysis uses SPSS with relevant statistical tests to validate findings.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Inclusion criteria

\- Age ≥ 60 years Histopathological diagnosis of lymphoma

Exclusion criteria

\- Presence of other concurrent active malignancies Uncontrolled diabetes mellitus with blood glucose \> 200 mg/dL at the time of PET/CT scan

Design outcomes

Primary

Measure	Time frame	Description
FDG-PET/CT Imaging Pattern Description in Elderly Lymphoma Patients	At time of initial PET/CT scan performed as part of routine clinical evaluation	The main outcome is the characterization of metabolic and anatomical findings from 18F-FDG PET/CT scans among elderly patients (≥60 years) diagnosed with lymphoma. This includes describing the visual appearance, extent, and distribution of disease lesions observed on initial imaging.

Outcome results