Closed Dysraphism, Dysraphism, Open Dysraphism
Conditions
Keywords
dysraphism, spina
Brief summary
Spinal dysraphisms are defined as a congenital malformation characterized by a defect in the closure of the neural tube in the caudal region. They are divided into two groups: open dysraphisms, where the skin covering is absent; and closed dysraphisms, where the skin abnormality is less obvious and diagnosis is sometimes more difficult. Both open and closed dysraphisms can cause a variety of neurological disorders, including urinary and fecal dysfunction, which is often more severe in open dysraphisms than in closed dysraphisms, which sometimes go unnoticed and may only become symptomatic during growth. As a result, urinary and fecal repercussions in closed dysraphisms are sometimes overlooked, and the literature on this subject remains scarce. The hypothesis is that a better understanding of the urinary and fecal repercussions of closed dysraphisms would allow for more appropriate and standardized follow-up of these children. The main objective of the study is to describe the urinary impact on children with spinal dysraphism, as well as how they are managed.
Interventions
Study of urinary and fecal impact of closed and dysraphism in the pediatric population
Sponsors
Study design
Eligibility
Inclusion criteria
* treated or cared for at Angers University Hospital for spinal dysraphism between January 1, 2014, and December 31, 2024
Exclusion criteria
* Differential diagnosis of dysraphism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of bladder dysfunction | up to 5 years | rate of bladder dysfunction in children with open or closed dysraphism |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fecal symptoms | up to 5 years | fecal symptoms that may be described by patients |
| Urinary treatments implemented | up to 5 years | urinary treatments that may be implemented during follow-up |
| Fecal treatments implemented | up to 5 years | fecal treatments that may be implemented during follow-up |
| Urinary symptoms | up to 5 years | urinary symptoms described by patients |
| Clinical signs | Baseline | linical signs that led to the diagnosis of dysraphism |
| general symptoms | Baseline | general symptoms that led to the diagnosis of dysraphism |
| Prenatal diagnosis | Baseline | presence or absence of a prenatal diagnosis |