Skip to content

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07256717
Acronym
BPIT_5LINE_369
Enrollment
369
Registered
2025-12-01
Start date
2025-10-10
Completion date
2026-02-25
Last updated
2025-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical Fitness

Keywords

Balanced Progressive Intensity Training, BPIT, 5-Line Principle, Movement Efficiency, Heart Rate Variability, Postural Control, Strength Training, Exercise Intervention, Neuromuscular Adaptation

Brief summary

This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force: Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact) The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.

Detailed description

Primary Outcome Measures Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5 Secondary Outcome Measures Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5 Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes Inclusion Criteria Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent Exclusion Criteria Recent injury (\<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste) MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No

Interventions

BEHAVIORALBalanced Progressive Intensity Training (BPIT) 5-Line Method

5-week supervised progressive training using the BPIT 5-Line framework developed by Dr. Neeraj Mehta.

Sponsors

BodyGNTX Fitness Institute
CollaboratorUNKNOWN
GFFI Fitness Academy
CollaboratorUNKNOWN
Indian Institute of Kinesiology and Biomechanics Science (IIKBS)
CollaboratorUNKNOWN
Bureau of Fitness Standards (BFS)
CollaboratorUNKNOWN
Active India Health & Fitness Trust (AIHFT)
CollaboratorUNKNOWN
Body Mechanic Chain of Gyms
CollaboratorUNKNOWN
Shri Mahaveer Ortho Clinic
CollaboratorUNKNOWN
Regain Fitness Zone
CollaboratorUNKNOWN
MMSx Authority Biomechanics Department
CollaboratorUNKNOWN
MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Masking description

Single-arm prospective interventional study

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications)

Exclusion criteria

* Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions

Design outcomes

Primary

MeasureTime frameDescription
Movement Efficiency Score (MES, 0-10)Baseline (Week 0) and end of study (Week 5)Change from baseline in the proprietary Movement Efficiency Score (MES), a validated composite metric of biomechanical function, movement quality, and postural alignment (derived from MMSx Flaw Checklist, visual/video analysis, and functional mapping).

Secondary

MeasureTime frameDescription
Range of Motion (ROM)Baseline and Week 5Change from baseline in joint range of motion (degrees) measured by goniometry at key sites (shoulder, hip, spine, ankle).
VAS Pain ScoreBaseline and Week 5Change from baseline in participant-reported pain/discomfort on a 0-10 Visual Analog Scale.
Strength IndexBaseline and Week 5Change from baseline in Strength Index calculated as Reps × Load (or estimated 1RM where applicable) for key movements.
Mobility Limitation (%)Baseline and Week 5Change from baseline in self-reported percentage limitation in daily functional tasks due to mobility restrictions.

Other

MeasureTime frameDescription
Heart Rate Variability (HRV - RMSSD)Baseline and Week 5Change from baseline in resting heart rate variability (RMSSD) as a biomarker of autonomic recovery.

Countries

India, United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026