Bone Density, Gut Microbiomes
Conditions
Brief summary
The study aims to understand the current situation of bone health in the Gannan Tibetan primary school student population, to explore the relationship between nutrition, intestinal microorganisms and bone health, to analyze the main factors affecting bone health from the perspective of nutrition and intestinal microecology, and to provide theoretical basis for the promotion and improvement of bone health in Tibetan primary school students.
Interventions
OTHERNo Intervention: Observational Cohort
No Intervention
Sponsors
Jianhua Ma
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
6 Years to 13 Years
Healthy volunteers
Yes
Inclusion criteria
* Tibetan primary school students currently enrolled in schools in Gannan Tibetan Autonomous Prefecture; Willing to participate and able to cooperate in completing bone density measurements; Additional inclusion criteria: Subjects who are 9 years old or older and agree to participate in dietary surveys and fecal sampling.
Exclusion criteria
Use of corticosteroid medications within the past year; Suffering from skeletal system diseases, metabolic disorders, or endocrine diseases; Additional
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dietary Characteristics | Day 1 | Dietary data were collected using a food frequency questionnaire (FFQ) to analyze dietary patterns and nutrient intake. |
| Bone density test | Day1 | In this study, a peripheral dual-energy X-ray absorptiometry (EXA-PRESTO) was used to measure the bone density of the non-dominant forearm of the subjects. |
| Fecal sample microbiological testing and analysis | Day 1 | This study entrusted Tianhao Gene Technology Co., Ltd. to perform the intestinal microbiome Accu16STM (16S rRNA absolute quantitative sequencing). The main research processes include DNA extraction, PCR amplification, library construction, and sequencing. |
Countries
China
Outcome results
None listed