Midline Laparotomy
Conditions
Brief summary
To compare the mean duration of postoperative analgesia following addition of dexmedetomidine to ropivacaine versus plain ropivacaine in ultrasound guided rectus sheath block in patients undergoing midline laparotomies
Interventions
PROCEDURERectus Sheath Block
In Dexmedetomedine combined with ropivacaine group, under ultrasound guidance, the needle will be advanced posterior to the rectus muscle, and 20 ml of 0.25% ropivacaine mixed with 1ug/kg body weight will be injected to hydrodissect the rectus muscle from the posterior sheath. In ropivacine only group, under ultrasound guidance, the needle will be advanced posterior to the rectus muscle, and 20 ml of 0.25% ropivacaine will be injected to hydrodissect the rectus muscle from the posterior sheath.
Sponsors
Quaid-e-Azam Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Patients with age 30 - 60 years. * Patients that will be scheduled for laparotomy under general anesthesia. * ASA (American Society of Anesthesiologist) s
Exclusion criteria
* Patient who will refuse for participation in study. * Infection at site of Rectus Sheath block. * History of any addiction. * Sensitivity to the local anesthetics. * Patient with pre-existing coagulation abnormalities INR more than 1.5.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean duration of analgesia | Baseline , 30 minutes , 2 hours, 4 hours , 6 hours , 8 hours , 12 hours , 24 hours | Assessed using the visual analogue score(VAS) ranging from 0-10 (0=no pain , 10= most severe unbearable pain) |
Countries
Pakistan
Outcome results
None listed