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LCMS-Based Metabolic Analysis Explores the Effect of American Ginseng on Urine and Plasma in Healthy Individuals

LCMS-Based Metabolic Analysis Explores the Effect of American Ginseng on Urine and Plasma in Healthy Individuals

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07252362
Enrollment
20
Registered
2025-11-26
Start date
2023-11-11
Completion date
2026-03-30
Last updated
2025-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Impact of American Ginseng on the Metabolomics of Urine and Plasma in Healthy Individuals

Keywords

American ginseng, metabolomics

Brief summary

Researchers will use LCMS Metabolic Analysis to Explore the Effect of American Ginseng on Urine and Plasma in Healthy Individuals Participants will: * Take 3 grams of American Ginseng powder every day for 14 days * Collect the fasting urine samples at the following times at the hospital: On the first day, on the 7th day after taking the medicine, and on the 14th day after taking the medicine. * Collect the fasting Serum samples at the following times at the hospital: On the first day and on the 14th day after taking the medicine. * Have their any adverse effects monitored and evaluated throughout the study.

Interventions

OTHERAmerican Gginseng

All the subjects took 3 grams of ginseng half an hour after breakfast every day for 14 consecutive days.

Sponsors

Zhejiang Cancer Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* 18 to 45 years old; * The subjects were fully informed about the research process and signed the informed consent form (the subjects had no abnormalities in routine physical examinations, no previous medical history, and no history of drug allergies); ③ During the trial, they were required to have a light diet and were prohibited from consuming alcoholic and caffeinated beverages;

Design outcomes

Primary

MeasureTime frameDescription
Urine metabolomicsFrom enrollment to the end of treatment at 2 weeksBy using LCMS Metabolic Analysis to Explore the Effect of American Ginseng on Urine in Healthy Individuals

Secondary

MeasureTime frameDescription
Plasma metabolomicsFrom enrollment to the end of treatment at 2 weeksBy using LCMS Metabolic Analysis to Explore the Effect of American Ginseng on plasma in Healthy Individuals.

Countries

China

Contacts

Primary Contactguan ai Bao, Master
doctorbga@126.com+8615968857341

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026