Sjogren Syndrome
Conditions
Keywords
Sjogren syndrome, temporamandibular joint
Brief summary
Study Purpose The purpose of this observational study is to determine the prevalence of temporomandibular dysfunction (TMD) in individuals diagnosed with Sjögren's syndrome and to examine the relationship between disease activity and TMD. The main question to be answered is: Is TMD more common in individuals with Sjögren's syndrome, and is there a relationship between disease activity and TMD? Method Participants diagnosed with Sjögren's syndrome will be evaluated. The prevalence and severity of TMD will be examined along with mouth opening, head posture, and oral health parameters.
Interventions
DIAGNOSTIC_TESTTemporomandibular Joint Function
Temporomandibular joint function and predictive parameters in patients with primary Sjögren Syndrome (pSS)
Sponsors
Pamukkale University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
-Inclusion Criteria Individuals between 18 and 65 years of age. Must have a confirmed diagnosis of Sjögren's Syndrome. Must possess the mental capacity and education to understand the significance of the research. Must be volunteers willing to participate in the study. -
Exclusion criteria
Incomplete questionnaires/scales. History of orthodontic treatment within the last six months. Presence of neurological or cognitive deficit. Patients with a history of pathology related to the temporomandibular joint (TMJ) and associated structures prior to the diagnosis of Sjögren's Syndrome.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fonseca Anamnestic Index (FAI) | Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period. | Assesses the severity of TMD. As the score increases, the TMD severity (none, mild, moderate, severe) worsens. (0-15: None, 20-45: Mild, 50-65: Moderate, 70-100: Severe) |
| EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) | Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period. | Evaluates disease activity. A high score (5 and above) indicates high disease activity. (The higher the average score, the more severe the symptoms of fatigue, pain, and dryness.) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analog Scale (VAS) for Disease Involvement | Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period. | Numerically evaluates the severity of specific symptoms like dry mouth, dry eyes, facial skin dryness, and lip dryness. As the score approaches 10, the severity of dryness reaches its highest level. |
| Xerostomia Inventory | Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period. | Measures the severity of dry mouth (xerostomia) symptoms. A higher score indicates more severe xerostomia symptoms. |
| Oral Health-Related Quality of Life - UK Scale | Evaluations started immediately after receiving ethics committee approval and will be completed within 6 months, which is the study period. | Assesses oral health-related quality of life. An increase in score generally indicates a greater deterioration in quality of life (i.e., worse oral health impact). |
Countries
Turkey (Türkiye)
Outcome results
None listed