Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease

Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease in Assiut University Child Hospital

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07247994

Enrollment

Registered

2025-11-25

Start date

2026-01-01

Completion date

2027-03-01

Last updated

2025-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IBD (Inflammatory Bowel Disease)

Keywords

Extraintestinal manifestations, Inflammatory bowel disease, Ibd

Brief summary

screen for neurologic and psychiatric disorders in children and adolescents with IBD.

Detailed description

Neurologic symptoms have a great importance in early diagnosis and treatment preventing major morbidity and later sequelae, especially if they precede GI symptoms The prevalence of neurologic manifestations of IBD varies between 0.2% and 36%. Their pathogenesis of neurologic manifestations in IBD consists of 6 mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents 3.infections complicating immune suppression 4.side effects of medications or iatrogenic as a surgical complication 5.thromboembolism 6.immunological factors UC patients are similar to or higher than CD patients in the probability of neurologic symptoms. Neurologic manifestations and complications include: headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures, neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating disorders and migraine

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

1 Years to 18 Years

Healthy volunteers

Inclusion criteria

* patients with IBD aged from from 1 to18 years old.

Exclusion criteria

* patients with IBD and aged above 18 years old or below 1 year old

Design outcomes

Primary

Measure	Time frame	Description
Screening for Neurological manifestations among children diagnosed with inflammatory bowel disease in Assiut university children hospital	during the period from January 2026 to January 2027.	Neurologic symptoms have a great importance in early diagnosis and treatment preventing major morbidity and later sequelae, especially if they precede GI symptoms The prevalence of neurologic manifestations of IBD varies between 0.2% and 36%. Their pathogenesis of neurologic manifestations in IBD consists of 6 mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents 3.infections complicating immune suppression 4.side effects of medications or iatrogenic as a surgical complication 5.thromboembolism 6.immunological factors UC patients are similar to or higher than CD patients in the probability of neurologic symptoms. Neurologic manifestations and complications include: headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures, neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating disorders and migraine
screen for neurologic and psychiatric disorders in children and adolescents with IBD.	1 year	—

Contacts

Primary ContactBishoy Shehata Faheem, Resident doctor

bishoyshehata116@gmail.com+201551312246

Outcome results