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Role of CT in Tetralogy of Fallot Diagnosis

Role of Computed Tomography in Diagnosis of Syndromic and Non Syndromic Tetralogy of Fallot

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07247435
Enrollment
37
Registered
2025-11-25
Start date
2025-11-15
Completion date
2028-09-15
Last updated
2025-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac CT TOF

Brief summary

To evaluate the role of MSCT in diagnosis and surgical planning in tetralogy of Fallot cases.

Detailed description

Role of Computed tomography (CT) : CT has become an indispensable imaging modality in the comprehensive evaluation and management of Tetralogy of Fallot (ToF). While echocardiography remains the initial diagnostic tool, CT offers unparalleled spatial resolution and the ability to generate high-quality, three-dimensional reconstructions of both intracardiac and extracardiac anatomy. This is particularly valuable for identifying associated anomalies such as major aortopulmonary collateral arteries (MAPCAs), anomalous coronary artery origins, and variations in pulmonary artery branching patterns that can significantly influence surgical decision-making. Preoperatively, CT enables precise assessment of the severity and extent of right ventricular outflow tract obstruction, ventricular septal defect morphology, and the relationship of the overriding aorta to the interventricular septum. Overall, CT complements other imaging modalities by providing a fast, accurate, and comprehensive anatomical roadmap that guides surgical planning, informs long-term follow-up, and aids in the early detection of complications. Its role is particularly pronounced in complex and syndromic cases of ToF, where anatomical variations are more common and precise preoperative mapping is critical for successful outcomes.

Interventions

DEVICEComputed tomography

Radiological device

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 12 Years
Healthy volunteers
No

Inclusion criteria

\- patients aged 1 day up to 12 years Confirmed diagnosis of tetralogy of Fallot. Patients with tetralogy of Fallot as apart from genetic syndrome.

Exclusion criteria

* Patients with other isolated congenital heart anomalies Previously operated cases of tetralogy of Fallot.

Design outcomes

Primary

MeasureTime frameDescription
Anatomical anomalies identification3 yearsIdentification cardiac and extra-cardiac anatomical anomalies

Contacts

Primary ContactBenyamin Gaballah
benyaminadel99@gmail.com01025303267
Backup ContactHassan Megaly, Professor
01006209584

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026