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Expanding Access to Safe Water in Nigeria

Expanding Access to Safe Water in Nigeria

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07246824
Enrollment
700
Registered
2025-11-24
Start date
2025-09-30
Completion date
2026-09-30
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chlorination

Keywords

Diarrhea, Health Systems

Brief summary

Access to safe water remains a pressing public health challenge in Nigeria, where 67% of the population lacks safely managed drinking water and waterborne diseases cause an estimated 70,000 child deaths annually. Building on evidence that point-of-use chlorination is highly cost-effective in reducing diarrheal disease, this study evaluates a scalable, community-based chlorine distribution model through a cluster-randomized controlled trial (RCT) in Kano State. Thirty communities across four Local Government Areas will be randomly assigned to one of three groups: (i) 20 treatment communities receiving community demonstrations and local chlorine redemption points, (ii) 10 control communities where no intervention will be conducted. After 3 months, 5 control communities will receive an individual-level sensitization and a voucher program and 5 will remain pure control communities. The RCT aims to estimate the causal impact of the community-based intervention on household chlorination rates, water quality (E. coli contamination), and knowledge of safe water practices over six months. By rigorously testing a community-led water treatment model, this study contributes new evidence on sustainable and cost-effective approaches to expand safe water access in low-resource settings. The results will inform national and regional strategies for scaling point-of-use chlorination across sub-Saharan Africa.

Interventions

BEHAVIORALCommunity Demonstrations

Facilitators will collaborate with local leaders, WASH officials and health facility staff in conducting community demonstrations introducing the chlorine product (WaterGuard+) to communities in the treatment group. Local leaders in the community will organize the meeting, while facilitators in the country will demonstrate how to use the product, what the correct dosage is, and explain the importance of water treatment. They will also show how village water is contaminated with Ecoli. These meetings will be targeted at eligible women (pregnant women and women with children under the age of 5), however all members of the community will be invited to attend. At the meeting, each attendee will be given one bottle of WaterGuard+, which is enough to treat drinking water for a household of 5 members for about a month, and 1,000 naira. Water Guard + is a 180g bottle of sodium dichloroisocyanurate (NaDCC) in granulated / powder form, produced and distributed by the Society for Family Health.

BEHAVIORALRedemption points

Study staff will set up at least one chlorine redemption point for each community. The location of the redemption point will be determined in consultation with the local community during Community Demonstrations. The redemption points could be health facilities, local shops/dispensaries/kiosks, local pharmacies, house of the village leader, CHW, or health staff or other suitable sites. Households will be able to visit the location and redeem a month's supply of a chlorine product. Distributors will use a redemption log to keep track of when participants redeem the chlorine product.

Sponsors

Princeton University
CollaboratorOTHER
University of Michigan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
Yes

Inclusion criteria

* Pregnant mothers and women with children under 5 children

Exclusion criteria

* Men, women with no children under 5 years old

Design outcomes

Primary

MeasureTime frameDescription
Treat drinking water with chlorine (tested in water sample)Measured up to 6 months of follow-upProportion of water samples with detectable chlorine in stored drinking water

Secondary

MeasureTime frameDescription
Presence of E.coliMeasured up to 6 months of follow-upProportion of water samples with detectable E.coli
Level of E.coliMeasured up to 6 months of follow-upLevel of E-coli (in log10 MPN/100ml) in water samples
Unsafe risk of ColiformMeasured up to 6 months of follow-upProportion of water samples with unsafe coliform ( \>100 colony forming units per 100mL)
Treat drinking water with chlorine (self-reported)Measured up to 6 months of follow-upProportion of women who reported using chlorine in the previous two days
Ever used chlorineMeasured up to 6 months of follow-upProportion of women who ever used chlorine
Last used chlorineMeasured up to 6 months of follow-upProportion of women who used chlorine yesterday or the day before
Heard about chlorineMeasured up to 6 months of follow-upProportion of women who ever heard about chlorine

Countries

Nigeria

Contacts

Primary ContactElisa Maria Maffioli, PhD
elisamaf@umich.edu4438754930

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026