Breast Cancer, Postoperative Acute Pain, Regional Anesthesia
Conditions
Keywords
Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block, Breast Cancer Surgery, Opioid Consumption, Pain Management
Brief summary
This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in patients undergoing breast cancer surgery. Both techniques are ultrasound-guided regional anesthesia methods targeting different interfascial planes of the thoracic wall. The study will evaluate postoperative pain scores, opioid consumption, Quality of recovery and potential complications. The findings are expected to contribute to optimizing regional anesthesia strategies for enhanced recovery and improved analgesia following breast cancer surgery.
Interventions
PROCEDUREInterpectoral-Pectoserratus Plane Block
Ultrasound-guided injection between pectoralis major-minor and pectoralis minor-serratus anterior planes.
PROCEDURESerratus Posterior Superior Intercostal Plane Block
Ultrasound-guided injection between the serratus posterior superior muscle and the intercostal muscles.
Sponsors
Zonguldak Bulent Ecevit University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* 18-65 years of age * ASA I-II-III risk groups * Patients with informed consent * Patients undergoing breast cancer surgery
Exclusion criteria
• Ages \<18 and \>65 * ASA ≥ IV * History of allergy to local anesthetics * Known coagulation disorders * Infection near the insertion site * Chronic analgesic use * Patients with diabetes mellitus and those receiving neoadjuvant chemotherapy (due to potential impairment of pain sensation) * Body mass index \>30 * Dementia or confusion * Lack of cooperation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cumulative opioid consumption | in the first 24 hours after completion of the surgical procedure | Cumulative opioid consumption in the first 24 postoperative hours after the completion of the surgical procedure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postsurgical Quality of Recovery measured by the Quality of Recovery questionnaire | first day after surgery | Postsurgical recovery by Quality of Recovery questionnaire (QoR-15) on first (D1) day after surgery. The minimum score on the Quality of Recovery questionnaire is 0 and the maximum score 150. Higher scores mean better quality of recovery. |
| Number of episodes of postoperative pain | In the first 24 hours after completion of the surgical procedure | Number of episodes of postoperative pain (NRS score ≥ 4) at rest and at deep inspiration in the first 24 postoperative hours after the completion of the surgical procedure |
Countries
Turkey (Türkiye)
Contacts
Primary Contactçağdaş baytar, MD
Outcome results
None listed