Primary Pterygium
Conditions
Keywords
Primary Pterygium, Compression Continuous Suture, Conventional Suture
Brief summary
To compare the advantages and disadvantages of continuous suture with suture and conventional Suture in primary pterygium surgery for autologous conjunctival graft fixation
Detailed description
Pterygium is an abnormal fibrovascular tissue hyperplasia disease that occurs in the conjunctiva. The pterygium tissue can break through the limbus of the corneosclera and grow into the cornea, causing a foreign body sensation in the eyes, astigmatism, decreased vision, and even restricted eye movement. The purpose of surgical treatment for pterygium is not only to remove the diseased tissue, but more importantly, to reduce the recurrence of pterygium after surgery. Pterygium excision combined with simple autologous conjunctival transplantation is currently the most commonly used method for treating pterygium. The recurrence rate after autologous conjunctival epithelial tissue transplantation can be reduced to 5% to 30%. As heterogenic substances, sutures can irritate the ocular surface, aggravate postoperative inflammatory reactions and conjunctival edema or hemorrhage, delay the repair of corneal wound epithelium, lead to abnormal ocular surface function, intensify postoperative discomfort, and induce hypertrophic granuloma or cysts, etc. Moreover, these adverse reactions can also induce the recurrence of pterygium (0-26%). In addition, the longer the time interval between suture removal, The greater the difficulty of removal, the more likely some of the knots may be completely buried under the conjunctiva. Therefore, in order to alleviate the adverse reactions caused by sutures and further simplify the operation of pterygium excision surgery, many attempts have been made at home and abroad to improve and innovate the method of graft fixation.
Interventions
PROCEDURECompression continuous suture with suture crimping
Pterygium excision combined with autologous conjunctival transplantation was performed, and the continuous suture method with pressure lines was adopted during the operation
PROCEDUREConventional Suture with suture crimping
Pterygium excision combined with autologous conjunctival transplantation was performed, and the traditional suture method was adopted during the operation
Sponsors
Tianjin Eye Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
1. Diagnosis of primary pterygium according to diagnostic criteria; 2. The pterygium head invades the cornea by 2-5mm; 3. The patient agrees to the surgical treatment and signs the surgical consent form.
Exclusion criteria
1. History of previous eye surgery; 2. Have active ocular inflammatory lesions; 3. recurrent and pseudopterygium; 4. The patient refuses surgery or is unable to have regular follow-ups
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of surgery | Intraoperative | The date on which the surgery was performed |
| Implant stability | Postoperative follow-up was performed 1 day and 1 week after surgery | Whether the conjunctival graft is loose or detached |
| Postoperative discomfort | Postoperative follow-up was performed 1 day and 1 week after surgery | The degree of discomfort after surgery was evaluated using the VAS Pain score Scale |
| Stitch removal time | Postoperative follow-up was performed 1 week after surgery | The date when the stitches were removed |
Countries
China
Contacts
Primary ContactYan Wang, director
Outcome results
None listed