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Knowledge About the Administration and Regulation of High Alert Medications Among Nurses in Mansoura University Children's Hospital: A Hospital-wide Audit

Pediatric Medication Safety Revolution: Auditing Nurses' Knowledge on High-Alert Drugs

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07243431
Acronym
HAM-Audit
Enrollment
335
Registered
2025-11-21
Start date
2025-02-12
Completion date
2025-09-12
Last updated
2025-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nurses' Knowledge of High-alert Medications in Pediatric Care

Keywords

high-alert medications, nurses knowledge, medication errors

Brief summary

This study checks how well nurses at Mansoura University Children's Hospital know about high-alert medications (HAMs). These are drugs that can cause serious harm if given incorrectly. We used a questionnaire to assess their knowledge and identify any gaps. The goal is to improve training and reduce medication errors in the hospital.

Detailed description

Background: Medication errors (MEs) are a major cause of patient harm, especially in pediatric settings. High-alert medications (HAMs) are drugs that carry a heightened risk of causing significant patient harm when used in error. Nurses play a critical role in the safe administration of HAMs. This hospital-wide audit aims to evaluate nurses' knowledge regarding the administration and regulation of HAMs at Mansoura University Children's Hospital. Objectives: 1. To assess the level of knowledge about HAMs among nurses. 2. To identify factors associated with sufficient knowledge of HAMs. Methods: A cross-sectional study was conducted using a self-administered questionnaire distributed to all nurses involved in medication administration at Mansoura University Children's Hospital. The questionnaire covered identification of HAMs, storage, administration protocols, and error prevention strategies. Data was collected from \[February to October 2025\] and analyzed using descriptive statistics and logistic regression. Setting: Mansoura University Children's Hospital, Mansoura, Egypt. Participants: All registered nurses working in the hospital and involved in medication administration. Outcome Measures: * Primary: Level of knowledge about HAMs (scored as sufficient/insufficient). * Secondary: Factors associated with sufficient knowledge (e.g., years of experience, training).

Interventions

None listed

Sponsors

Omar Hamdy
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* \- Registered nurses working at Mansoura University Children's Hospital. * Involved in medication administration. * At least 6 months of experience in the hospital.

Exclusion criteria

* Non-nursing staff. * Nurses not involved in direct patient care or medication administration.

Design outcomes

Primary

MeasureTime frameDescription
Proportion of nurses with sufficient knowledge of high-alert medicationsFebruary 2025 to October 2025Percentage of nurses scoring ≥70% on the questionnaire assessing knowledge of high-alert medications (identification, administration, storage, and error prevention).

Secondary

MeasureTime frameDescription
Factors associated with sufficient knowledge of high-alert medicationsFebruary 2025 to October 2025Identification of factors (e.g., years of experience, training, department) associated with scoring ≥70% on the knowledge questionnaire using multivariate logistic regression.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026