NAFLD and NASH, NAFLD Cirrhosis, NAFLD( Non-alcoholic Fatty Liver Disease )
Conditions
Brief summary
To establish a cohort of elderly fatty liver disease based on the community medical examination population. Through the large-scale cohort study, the risk factors affecting fatty liver in the elderly will be explored in depth from the aspects of lifestyle, environment and genetics, the development pattern and mechanism of fatty liver in the elderly will be analysed, and the health risk assessment system and Chinese standard for fatty liver in the elderly covering cardiovascular risk, risk of hepatic fibrosis and risk of sarcopenia will be established, so as to provide the scientific basis for the precise intervention of fatty liver in the elderly in China.
Interventions
None listed
Sponsors
The Affiliated Hospital of Hangzhou Normal University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
* ① Elderly people aged ≥65 years among permanent residents (living for more than 5 years) in the survey area; * Imaging diagnosis (ultrasound or FibroScan/FibroTouch) of fatty liver; -③ Voluntary participation in this study and signing an informed consent form.
Exclusion criteria
* ①Major disability, mental illness, major wasting disease, severe cardiac, pulmonary and renal insufficiency; * Patients with combined primary liver cancer or other types of cancer; -③Patients who have received liver transplant or other organ transplants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of liver fibrosis | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of cardiovascular disease | 2 years |
| Incidence of sarcopenia | 2 years |
Countries
China
Contacts
CONTACTWei Zhang, DR
Outcome results
None listed