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Short-Term Rhodiola Rosea: Effects on Hoops Players' Game Time, Fatigue & Performance

The Effect of Short-term Rhodiola Rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07239960
Enrollment
48
Registered
2025-11-20
Start date
2024-06-22
Completion date
2024-12-20
Last updated
2025-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Rhodiola, Sports Performance, Fatigue, Basketball Players, Exercise Physiology, Physical Performance

Brief summary

This study aims to evaluate the effects of short-term Rhodiola rosea supplementation on simulated game performance, perceived fatigue, and aerobic capacity in basketball players. The participants will include 48 professional male basketball players aged 18-25 years, all from Beijing Sport University and holding at least a national level-2 athlete certification. The key research questions are as follows: Does Rhodiola rosea supplementation improve the total completion time of simulated games? Does it reduce post-simulation heart rate and perceived fatigue while enhancing aerobic capacity (e.g., maximal oxygen uptake) and antioxidant indicators? To address these questions, researchers will compare the Rhodiola rosea supplementation group (RHO group) with the control group (CTR group). Participants will be required to: Consume Rhodiola rosea supplements or placebos (empty capsules) daily for 28 consecutive days on an empty stomach. Complete simulated game tests-including sprints, defensive slides, and layups-with total completion time and heart rate recovery recorded. Provide blood samples for the measurement of biochemical indicators such as total antioxidant capacity, superoxide dismutase activity, and creatine kinase. Complete a series of physical fitness tests, including the countermovement jump (CMJ) test, 5-km run, YO-YO Intermittent Recovery Test, and maximal oxygen uptake (VO₂max) test.

Detailed description

This study is a randomized, controlled, double-blind clinical trial aimed at evaluating the effects of short-term Rhodiola rosea supplementation on simulated game performance, perceived fatigue, physical fitness indicators, and biochemical parameters in professional basketball players. The study participants included 48 male basketball players from Beijing Sport University, all of whom were national level 2 athletes or above, ensuring a consistent training background and sports experience. The experimental design employed a strict randomization method, dividing participants into a Rhodiola rosea supplementation group (RHO group) and a control group (CTR group), with double-blind measures implemented to minimize potential bias. For example, the RHO group received a daily dose of 2.4 g of Rhodiola rosea extract (containing 0.5 g of salidroside per 100 g of raw material), while the CTR group consumed identical-looking empty capsules. All supplements were administered in a fasted state, twice daily, 30 minutes before breakfast and lunch, accompanied by an equal volume of water to control for placebo effects. Additionally, participants' daily dietary intake, including total calories, carbohydrates, proteins, and fats, was recorded throughout the study period to exclude nutritional factors as potential confounders. In terms of experimental procedures, participants first completed baseline health assessments and physical measurements, followed by a 28-day supplementation period. Key testing sessions included simulated game testing, physical fitness tests, and blood sample collection. The simulated game test record the total time taken by participants to complete the simulated game, which includes common on-court movements such as sprints, defensive slides, and step-backs. Physical fitness tests covered multiple dimensions: the vertical jump test (CMJ) ; the YO-YO intermittent recovery test; the maximal oxygen uptake (VO₂max) test; the 5 km running test; heart rate monitoring used Polar HR monitors, with data recorded before and after tests to assess fatigue recovery. Blood sample collection was conducted before the simulated game, with participants fasting for 8-12 hours. Venous blood samples were collected uniformly between 8:00 and 8:30 AM, followed by centrifugation to separate plasma and red blood cells, which were stored at -80°C for subsequent analysis. Biochemical indicators included plasma total antioxidant capacity (TAC) and superoxide dismutase (SOD) activity, malondialdehyde (MDA) concentration, and creatine kinase (CK) activity. Data analysis was performed using SPSS software (version 26) and GraphPad Prism (version 9.0), with continuous variables presented as mean ± standard deviation. Normality was assessed using the Shapiro-Wilk test, and a 2×2 mixed-design ANOVA \[group (CTR vs. RHO) × time (pre-test vs. post-test)\] was employed to evaluate intervention effects.

Interventions

DIETARY_SUPPLEMENTRhodiola rosea, L

Participants in this arm will receive daily capsules containing Rhodiola Rosea for 28 days. The capsules are identical in appearance to placebo capsules. The intervention aims to evaluate the effects of Rhodiola supplementation on basketball players' simulated game performance, sprint times, perceived fatigue, aerobic capacity, and antioxidant markers. Participants will undergo baseline and post-intervention physical fitness assessments, including sprint tests, endurance tests, Countermovement Jump (CMJ), heart rate recovery, and simulated game tasks.

OTHERPlacebo Comparator

Participants in this arm will receive daily placebo capsules (identical in appearance to Rhodiola capsules) for 28 days. This group serves as a control to compare the effects of Rhodiola supplementation on basketball players' simulated game performance, sprint times, perceived fatigue, aerobic capacity, and antioxidant markers. Participants will complete the same baseline and post-intervention physical fitness assessments as the experimental group.

Sponsors

Beijing Sport University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Intervention model description

This study uses a randomized, double-blind, parallel-group design. Participants are randomly assigned to either the Rhodiola supplementation group or the placebo group, and both groups receive their respective interventions simultaneously for 28 days.

Eligibility

Sex/Gender
MALE
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Male basketball players aged 18 years or older * National Level 2 athletes or above with training experience * Voluntarily participating and providing written informed consent * Healthy, without chronic diseases, neuromuscular or musculoskeletal disorders, cardiovascular diseases, or diabetes * Not using other nutritional supplements or alcohol-containing products during the study, and non-smokers

Exclusion criteria

* Allergy to Rhodiola or study-related substances * Recent major surgery or injury affecting athletic performance * Use of antidepressants or stimulant drugs * Unable to comply with training or intervention requirements during the study * Any other condition that may compromise safety or data reliability

Design outcomes

Primary

MeasureTime frame
Total completion time of the simulated gameBaseline and after 28 days of supplementation

Secondary

MeasureTime frame
Heart rate recoveryBaseline and after 28 days of supplementation
Total distance in the YO-YO intermittent recovery testBaseline and after 28 days of supplementation
Countermovement jump (CMJ) heightBaseline and after 28 days of supplementation
Maximal oxygen uptake (VO₂max)Baseline and after 28 days of supplementation
5 km running timeBaseline and after 28 days of supplementation
Rating of Perceived Exertion (RPE)Baseline and after 28 days of supplementation
Superoxide dismutase (SOD) activityBaseline and after 28 days of supplementation
Malondialdehyde (MDA) concentrationBaseline and after 28 days of supplementation
Creatine kinase (CK) activityBaseline and after 28 days of supplementation
BMI(kg/m^2)Baseline and after 28 days of supplementation
Plasma total antioxidant capacity (TAC)Baseline and after 28 days of supplementation

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026