Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study

Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction: A Comparative Clinical Stud

Status

Enrolling by invitation

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07239024

Enrollment

Registered

2025-11-20

Start date

2025-12-01

Completion date

2026-04-20

Last updated

2025-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement

Brief summary

Comparison of piezocisin and injectable platelets rich fibrin during canine retraction

Detailed description

Evaluation of piezocision versus injectable platelet-rich fibrin during orthodontic canine retraction: A comparative clinical study

Interventions

PROCEDUREIprf and piezocision

Injection of iprf and piezocisin

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

14 Years to 22 Years

Healthy volunteers

Yes

Inclusion criteria

. An age ranges from 14-22 years. 2. Crowding or protrusion that require 1st premolars extraction, followed by symmetrical canine retractions. 3\. All permanent teeth present, 3rd molars aren't considered. 4. Good oral hygiene. 5. No systemic disease and/or medication that could interfere with orthodontic tooth movement. 6. No previous orthodontic treatment. 7. No evidence of craniofacial anomalies, such as cleft lip and palate or previous history of trauma, bruxism, or parafunction. 8. No tooth size, shape, or root abnormalities visible on patient's radiographic records. \-

Exclusion criteria

Patients diagnosed to have an indication for non-extraction approach. 2\. Poor oral hygiene or periodontally compromised patient. * 3\. Previous orthodontic treatment. 4. Any implanted assistive (e.g., pacemakers, cochlear implants, etc.). 5. Any skeletal dysplasia or craniofacial malformation. 6. Patients with root resorption, impacted canine or dental anomalies. 7. Any systemic diseases or medications that could interfere with orthodontic tooth movement.

Design outcomes

Primary

Measure	Time frame
Rate of canine retraction	4 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026