Multiple Sclerosis
Conditions
Keywords
multiple sclerosis, electromyography, urinary incontinence, pelvic floor, fatigue
Brief summary
The study aimed to explore the link between urinary incontinence (UI) severity in patients with multiple sclerosis (PwMS), electromyography (EMG) findings, and other relevant factors.
Detailed description
The study will consist of a cross-sectional observational analysis involving a cohort of 47 PwMS. The assessment will be employed various instruments, including the Expanded Disability Status Scale (EDSS), Neurogenic Bladder Symptom Score (NBSS), International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), Incontinence Impact Questionnaire (IIQ-7), International Physical Activity Questionnaire (IPAQ), Fatigue Severity Scale (FSS), EMG.
Interventions
None listed
Sponsors
Artvin Coruh University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 50 Years
Inclusion criteria
* having an MS diagnosis according to the 2017 revised McDonald criteria, * experiencing symptoms of UI as defined by the International Continence Society (ICS), * having an EDSS score below 6.5, * PwMS with no communication issues.
Exclusion criteria
* PwMS who did not give consent to participate, * those with medication changes in the past 6 months, * pregnant PwMS, * recent vaginal or caesarean deliveries within 6 months, * pelvic organ prolapse, * urinary tract infection, * recent attack history in the past month.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Expanded disability status scale (EDSS) | Single assessment at enrollment | The Expanded disability status scale (EDSS) will be assessed disability and progression in PwMS, with scores from 0 (normal neurological exam) to 10 (death from MS). Higher scores indicate greater disability. |
| Neurogenic Bladder Symptom Score (NBSS) | Single assessment at enrollment | Storage, voiding, and complication symptoms of neurogenic bladder will be assessed with the Neurogenic Bladder Symptom Score (NBSS), a 24-item questionnaire covering incontinence, storage and voiding, and outcomes. |
| International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) | Single assessment at enrollment | The frequency and amount of leakage will be assessed using a six-item scale, and urinary incontinence will be categorised into four groups: mild (1-5), moderate (6-12), severe (13-18) and very severe. |
| Incontinence Impact Questionnaire (IIQ-7) | Single assessment at enrollment | Urinary symptoms' impact on daily activities was assessed with the Incontinence Impact Questionnaire (IIQ-7). The 7-item Likert scale has a score range of 0-21, with higher scores reflecting an increased negative impact of incontinence on social functioning, quality of life, and physical activity. |
| Pelvic Floor Muscle Activity | Single assessment at enrollment | An electromyography (EMG) device with surface electrodes will be used to assess pelvic floor muscle (PFM) activity. Patients received training beforehand, and measurements were taken noninvasively with two electrodes around the perineum and vagina and one on the inner thigh in women. |
| International Physical Activity Questionnaire (IPAQ) | Single assessment at enrollment | The International Physical Activity Questionnaire (IPAQ) assesses the frequency and duration of vigorous, moderate, and walking-like activities over a week. The values are multiplied by factors of 8, 4, and 3.3 Metabolic Equivalent of Tasks, respectively, to help measure overall physical activity. The minimum score for the IPAQ is 0, while there is no theoretically determined maximum score. Higher scores are associated with the individual engaging in a higher level of physical activity. |
| Fatigue severity scale (FSS) | Single assessment at enrollment | Fatigue severity scale (FSS) assesses fatigue severity in MS with nine items rated on a 7-point Likert scale. The mean score, adapted to Turkish society, indicates pathological fatigue if it is 4 or higher. |
Countries
Turkey (Türkiye)
Contacts
CONTACTZeynep Yıldız Kızkın
PRINCIPAL_INVESTIGATORZeynep Yıldız Kızkın
Artvin Coruh University
Outcome results
None listed