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ARISe at UMass Chan

ARISe at UMass Chan: Remote Eye Tracking Study of Vaccine Messaging in Rural Populations

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07236034
Acronym
ARISe
Enrollment
700
Registered
2025-11-19
Start date
2025-12-01
Completion date
2026-12-30
Last updated
2026-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaccination, Vaccination Promotion

Keywords

Message perceptions, Vaccination, Immunization

Brief summary

The goal is to identify the most impactful strategies for capturing attention and enhancing effectiveness of vaccine promotion messages. This will be done using an online survey that employs remote eye-tracking and self report measures to evaluate response to sample vaccine promotion social media content in rural populations in New England. Participants will be randomly assigned into one of 14 conditions in a 2(source: expert vs. influencer) by 7 (themes: constructs from 7C Vaccine Framework) experiment and view sample messages and then answer questions about their attitudes and beliefs while being monitored for eye-tracking.

Interventions

BEHAVIORALExposure to source and message content

Within each arm, participants will be exposed to two messages each of which are delivered by the same source (peer or professional) and have message content related to one of the 7C Constructs.

Sponsors

University of Massachusetts, Worcester
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Investigator)

Intervention model description

Participants will be assigned to one of 14 conditions and view two messages within each.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age 18+ * Living in New England state (CT, MA, ME, NH, VT RI) in a zip code as defined by each individual state's definition of rural * Able to read and write in English * Access to an internet connected computer or laptop with a web-camera

Exclusion criteria

* N/A

Design outcomes

Primary

MeasureTime frameDescription
Source credibilityImmediately after viewing each messageParticipants' perception of the credibility of the message source will be assessed using a 7-point Likert scale measured across four items. Participants will be asked to rate the following four items on this scale: To what extent do you believe the source of the message to be… (1=not at all, 7=very much so) 1. Fair 2. Accurate 3. Telling the whole story 4. Trustworthy Unit of measure: Scale score 1-7, mean
Perceived Message EffectivenessImmediately after viewing each messagePerceived message effectiveness will be measured using six items (worth remembering, grabs attention, powerful, informative, meaningful, convincing), each rated on a 7-point Likert scale. The outcome will be the mean of these six ratings for each participant, then averaged by experimental condition. To what extent is… (1=not at all, 7=very much so) 1. The message worth remembering 2. The message grabs attention 3. This message powerful 4. This message informative 5. This message meaningful 6. This message convincing Unit of Measure: Scale score (1-7, mean across items)
Visual attentionDuring message viewing ( immediately post-randomization, prior to completion of post-message survey)Visual attention, quantified as mean dwell time in milliseconds, will be measured using remote eye-tracking while participants view vaccine promotion messages. Dwell time will be calculated for pre-specified Areas of Interest (AOIs) during the message viewing period. Higher dwell times indicate greater visual attention to the AOIs. Unit of measure: mean dwell time in milliseconds per message
Message reactanceImmediately after viewing each messageReactance will be assessed using four items (irritated, angry, annoyed, aggravated), rated 0 ("None of this feeling") to 4 ("A great deal of this feeling"). The mean reactance score will be calculated for each participant. How much did this message make you feel the following way? Response options: 0 (None of this feeling) to 4 (A great deal of this feeling). 1. Irritated 2. Angry 3. Annoyed 4. Aggravated Unit of Measure: Scale score (0-4, mean across items)
Information sharing intentionsImmediately after viewing each messageDescription: Assessed with 6 items regarding interpersonal and online sharing, rated 1 (Strongly disagree) to 5 (Strongly agree). The mean score across items will be reported per participant and per condition. Rate with the following statements on a scale from 1 (Strongly disagree) to 5 (Strongly agree). Interpersonal setting 1. I would be willing to share this information with others. 2. I would talk with others about this message. 3. I would point others in a direction where they could read this message. Online setting 4. I would be willing to post a link to this information on my social media. 5. I would like a social media post with this information. 6. I would share a social media post with this information. Unit of Measure: Scale score (1-5, mean across items)

Secondary

MeasureTime frameDescription
Vaccine perceptionsAssessed at baseline (prior to message exposure) and immediately post-intervention (after message exposure)Vaccine perceptions will be measured using an 8-item scale, administered pre- and post-message exposure. Items are rated from 1 (Strongly disagree/very negative) to 7 (Strongly agree/very positive). Higher scores indicate more positive vaccine perceptions. The outcome will be the mean change in score from pre- to post-exposure. Unit of Measure: Scale score (1-7, mean change)

Countries

United States

Contacts

CONTACTGrace W Ryan, PhD, MPH
grace.ryan1@umassmed.edu508-859-0179
PRINCIPAL_INVESTIGATORGrace W Ryan, PhD, MPH

University of Massachusetts, Worcester

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 8, 2026