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Deep Learning-Based Multidimensional Body Composition Mapping for Outcome Prediction in HCC Patients Undergoing TACE

Deep Learning-Based Multidimensional Body Composition Mapping for Predicting Clinical Outcomes in Hepatocellular Carcinoma Patients Undergoing TACE

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07235410
Enrollment
300
Registered
2025-11-19
Start date
2025-11-01
Completion date
2026-11-01
Last updated
2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Brief summary

Hepatocellular carcinoma (HCC) is a common liver cancer, and many patients cannot receive surgery. For these patients, transarterial chemoembolization (TACE) is an important treatment. However, patients often respond differently to TACE, and it is difficult to predict who will benefit most. This study uses deep learning to automatically analyze routine CT images taken before TACE. By measuring body composition features, such as the size and condition of different abdominal organs and tissues, we aim to better understand patients' overall health status and treatment tolerance. The goal is to develop a prediction model that can help doctors estimate survival and treatment outcomes more accurately. This may assist in making more personalized treatment decisions and improving patient care.

Interventions

None listed

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

1. Patients diagnosed with Hepatocellular Carcinoma from January 1, 2018 to May 31, 2024; 2. Age \> 18 years old.

Exclusion criteria

1. Poor image quality; 2. Loss of follow-up; 3. Presence of another type of malignant tumor other than liver cancer; 4. Incomplete medical records.

Design outcomes

Primary

MeasureTime frame
OSAfter the TACE procedure until May 1, 2025

Secondary

MeasureTime frame
PFSAfter the TACE procedure until May 1, 2025

Countries

China

Contacts

Primary ContactYuanyuan Chu
whunionlunli@126.com+8602785726375

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026