Pregnancy
Conditions
Keywords
Pesticides, organic vegetables
Brief summary
Numerous studies have highlighted the harmful effects of pesticide exposure during the prenatal period. Food is one of the main vectors of exposure to pesticides, particularly glyphosate, which is the most widely used herbicide. Observational studies have highlighted their effects on health, but few interventional studies have been conducted to identify effective interventions to reduce or eliminate environmental risks. In 2022, the City of Strasbourg implemented the Ordonnance Verte (Green Prescription) program, giving all pregnant women in the city access to a weekly basket of organic and local vegetables for several months, as well as awareness-raising workshops on endocrine disruptors and healthy eating. The objective of this study is to assess whether this type of program reduces pregnant women's exposure to pesticides compared to women who continue to eat according to their usual habits. If conclusive, this type of assessment would play a key role in facilitating the rollout of similar initiatives on a larger scale and protecting the health of pregnant women and future children.
Interventions
BEHAVIORALConsumption of organic vegetables
Consumption of organic vegetables or non-organic for control group (according to their usual habits) for 2 weeks
Sponsors
University Hospital, Strasbourg, France
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Be a woman * Be less than 32 weeks pregnant * Be registered with the Ordonnance Verte program * Have agreed, when registering for the program, to be contacted by a research team * Be affiliated with a social security system or be a beneficiary of such a system. * Be fluent in French. * Be over 18 years of age * Be able to understand the objectives and risks associated with the research and give dated and signed informed consent * Have a telephone and internet access
Exclusion criteria
* Participation in a study on nutrition or any other studies likely to affect exposure to the compounds under investigation * Inability to provide informed consent (difficulties in understanding on the part of the pregnant woman, etc.) * Being under judicial protection * Being under guardianship or conservatorship * Working in the agricultural sector (farmer, employee, apprentice) * Living with someone who works in the agricultural sector (farmer, employee, apprentice)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in urinary pesticide concentrations over the two-week study period in the intervention group | Day 0 and at 2 weeks | Measured as the difference in pesticide levels before and after the intervention |
| Difference in urinary pesticide concentrations between the two groups | Day 0 and at 2 weeks | Measured as the difference in pesticide levels in intervention vs. control groups |
Countries
France
Contacts
Primary ContactVirginie COLLIN-BUND, MD
Outcome results
None listed