Irreversible Pulpitis
Conditions
Keywords
Effect of dexamthasone on irreversible pulpitis
Brief summary
This randomized controlled trial aims to compare the effectiveness of supra periosteal injection of dexamethasone versus placebo in reducing post operative pain in teeth diagnosed with symptomatic irreversible pulpitis. A total of 44 patients will be randomly assigned into two groups: Group A will receive a supra periosteal injection of dexamethasone(4mg/ml), and Group B will receive a similar injection of normal saline as placebo. post operative pain will be assessed at 6hr,24hr and 48hr using a VAS Analogue Scale, with the final outcome measured at 24hrs. the study will help determine whether local dexamethasone injection is effective in minimizing postoperative pain
Interventions
particappant in this group will receive a supraperiosteal injection of dexamethasone 4mg/ml at the mucbuccal fold before endodontic treatment of teeth with symptomatic irreversible pulpitis
DRUGNormal saline injection
particapant in this group will receive a supraperiosteal injection of normal saline at mucobuccal fold in the similar manner and volume as the experoimental drug
Sponsors
College of Physicians and Surgeons Pakistan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients age 18 or above 18 year old (to have complete apex formation) * Patient with normal periapical area (no pain on percussion). * Patient who have not received any preoperative analgesic and antibiotic in last one month.
Exclusion criteria
* Pregnancy and Lactation because radiographs are contraindicated. * Moderate to severe periodontal disease because teeth are not salvageable. * Patient with nonvital teeth diagnose via cold test and EPT. * Patient with known sensitivity to dexamethasone by history. * Patients whose medical history include a history of certain illnesses, such as HIV, heart disease, or epilepsy (conditions that can affect a patient's rate of healing).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post operative pain | 24hr after endodontic treatment | Pain will be measured using a 10 - point Visual Analogue Scale where 0=no pain, 1-3=mild pain, 4-6= moderate pain, and 7-10 = severe pain the absence of pain will be considered as effective treatment |
Countries
Pakistan
Outcome results
None listed