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Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period

Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period of Pediatric OSAS Surgery Under General Anesthesia, Randomized Controlled Trial

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07231887
Enrollment
262
Registered
2025-11-17
Start date
2026-01-31
Completion date
2026-07-31
Last updated
2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxia

Brief summary

Pediatric Obstructive Sleep Apnea Syndrome (OSAS) is common, often due to enlarged tonsils/adenoids. Tonsillectomy/adenoidectomy frequently performed under GA with tracheal intubation due to the age of children. Risk of hypoxemia and respiratory complications during the peri-extubation period is high.

Detailed description

The most common disorder of sleep apnea in children is obstructive sleep apnea syndrome (OSAS), characterized by interrupted breathing and partial or complete obstruction of the upper airway, the main factor is the enlargement of the tonsils and adenoids in the pediatric pharynx. The clinical symptoms are snoring, and open-mouth breathing, then resulting in hypoventilation and hypoxemia. Due to the age of children, tonsillectomy and adenoidectomy are often performed under general anesthesia with tracheal intubation. The risk of hypoxemia and the degree of oxygen saturation reduction are bigger when the mask was removed in the supine position, and the most serious complication also occurred in the supine position. Therefore, the lateral position is preferable to the supine position for mask removal. There are few reports on the effect of different positions on complications related to tracheal extubation after tonsillectomy and adenoidectomy under general anesthesia in children with OSAS. In this study, we will investigate and compare whether the use of lateral position or semi-prone position impact on the occurrence of choking, agitation, decreased pulse oxygen saturation - (SpO2) and the oral and nasal secretions during the awakening period.

Interventions

PROCEDUREpositioning during peri-extubation

investigate and compare whether the use of lateral position or semi-prone position impact on the occurrence of choking, agitation, decreased pulse oxygen saturation - (SpO2) and the oral and nasal secretions during the awakening period.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
2 Years to 10 Years
Healthy volunteers
No

Inclusion criteria

* Age 2-10 years * American Society of Anesthesiologists physical status classification (ASA) I - II * Patients scheduled for ENT procedures involving tonsillectomy, adenoidectomy or adenotonsillectomy

Exclusion criteria

* • Patient legal guardian refusal to participate in the study. * Children with cardio-pulmonary disease

Design outcomes

Primary

MeasureTime frameDescription
Incidence of hypoxemic events in the peri-extubation periodone hour after extubationHypoxemic events which last \> 2 seconds after extubation will be recorded when Spo2 is less than 94% on room air.

Secondary

MeasureTime frameDescription
Incidence of respiratory complicationsone hour after extubationIncidence of respiratory complications such as choking, laryngospasm, posterior tongue drop.

Contacts

Primary ContactShimaa A. Abbas
Shimaa.abbas@med.aun.edu.eg01002953253
Backup ContactMohammed R. Mahmoud
drabugabal2008@gmail.com01120792510‬‬‬‬‬‬

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026