Detection of Microplastics in Patients With Periodontitis

Detection of Microplastics in Patients With Periodontitis - a Cross-sectional Study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07231198

Acronym

micropl_perio

Enrollment

Registered

2025-11-17

Start date

2026-02-01

Completion date

2028-02-01

Last updated

2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases, Periodontitis

Keywords

periodontitis, microplastics

Brief summary

Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults aged 18 and over * Gender: Female / male / diverse * Patients * who have been diagnosed with stage III and IV periodontitis. * who have not yet started periodontal treatment. * who still have at least 20 teeth. Providing written consent to participate in the study.

Exclusion criteria

* Patients * who have already been treated for periodontitis * who have already undergone/begun periodontitis treatment

Design outcomes

Primary

Measure	Time frame	Description
Microplastics	one year	number of patients with periodontitis with microplastics in periodontal pockets, quantification of microplastic particles in periodontal pockets, qualitative analysis of microplastic

Contacts

Primary ContactHady Haririan, Univ.-Prof., Dr., PhD, MSc

hady.haririan@med.sfu.ac.at+4317201966

Outcome results