Very Low Birth Weight Infant
Conditions
Brief summary
Local data on the neonatal outcomes in early versus late trophic feeding in preterm very low birth weight neonates in terms of mean hospital stay is scarce. Therefore, the current study was planned with the objective of comparing the neonatal outcomes in early versus late trophic feeding in preterm very low birth weight neonates in terms of mean hospital stay.
Detailed description
Since preterm, very low birth weight births are common in society, an effective treatment modality is needed at the moment. Evaluating the length of hospital stay and occurrence of necrotizing enterocolitis in preterm very low birth weight neonates with respect to two approaches of trophic feeding in local settings will provide an insight into a better implementation of preventive strategies, resulting in reducing the hospital stays and the incidence of necrotizing enterocolitis, and hence reducing the burden on the already meager resources.
Interventions
DIETARY_SUPPLEMENTEarly trophic feeding
Infants will receive trophic (enteral) feeding within the first 48 hours after birth.
DIETARY_SUPPLEMENTLate trophic feeding
Infants will receive trophic (enteral) feeding within the first 72 hours after birth.
Sponsors
RESnTEC, Institute of Research
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Days to 30 Days
Healthy volunteers
No
Inclusion criteria
* Any gender * Neonates aged 1-30 days * Preterm very low birth weight neonates
Exclusion criteria
* Neonates transferred from other hospital and already started on antibiotics. * Neonates with congenital anomalies, hypoxic ischemic encephalopathy, central nervous system (CNS) impairment, neonatal sepsis, urinary tract infection, or one of twins or higher order multiples (on history and medical record). * Non-consenting parents.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of necrotizing enterocolitis | Up to 30 days | Confirmation of the occurrence of necrotizing enterocolitis based on modified Bell's diagnostic criteria |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital stay | through study completion, an average of 1 month | Total days from admission till final outcome (discharge/death due to any case). |
Countries
Pakistan
Outcome results
None listed