Urinary Tract Infection (Diagnosis)
Conditions
Brief summary
The aim of this study is to compare between effect of empirical antibiotic prophylaxis versus enhanced prophylactic measures on rate of urinary tract infection after Flexible ureteroscopy in Children.
Interventions
empirical antibiotic vs urine culture guided antibiotic
DEVICELevofloxacin
culture based antibiotic
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
4 Years to 14 Years
Healthy volunteers
Yes
Inclusion criteria
* Age starting from 4 up to 14 years old. * Patients with renal stones from 1cm to 1.5cm in largest dimensions (not more than 4 cm3 measured by CTUT) undergoing flexible URS.
Exclusion criteria
* Patients who refuse to participate in the study. * Patients with single functioning kidney. * Patients with rising serum creatinine. * Known patient with neurogenic bladder. * Patients with DM type1. * Immunocompromised children. * Children with coagulopathy. * Patients with untreated UTI (or any interfering symptoms with UTI as fever or irritative LUTS).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreased rate of urinary tract infection after Flexible ureteroscopy in Children | From enrollment to the end of treatment at 2 weeks |
Countries
Egypt
Outcome results
None listed