Stroke Osteoporosis
Conditions
Brief summary
The aim of this study is to evaluate the effect of these factors and stroke itself on osteoporosis developing after stroke. Thus, the expected benefit of the study is to contribute to the identification and determination of the need for treatment in high-risk patients through further studies. There are no expected risks from the study.
Interventions
Patients who have had a stroke and are at risk of fracture, and for whom routine assessment requires Bone Mineral Density (BMD) testing, will be included in the study. In addition, patients who have already undergone BMD testing for osteoporosis screening and who present to the outpatient clinic, with similar age and comorbidities, will be screened from the system, and 28 non-stroke patients who agree to participate will be included in the study.
Sponsors
Study design
Eligibility
Inclusion criteria
1. Followed by ischemic or hemorrhagic stroke 2. Between 1 week and 6 months or \>1 year has passed since the date of the event 3. Being between 55 and 85 years of age
Exclusion criteria
1. The patient has additional neurological conditions besides stroke 2. The patient has a psychiatric condition 3. History of recurrent stroke 4. BMD scan performed within the last year for stroke patients 5. Having received osteoporosis treatment before or after the stroke 6. The patient having a fragility fracture before the stroke 7. The patient having a hip fracture or hip prosthesis 8. The patient having an additional condition that affects physical function before the stroke (amputation, severe fracture) 9. The patient has an additional disease or medication use that could cause secondary osteoporosis 10. The patient's stroke did not cause physical function loss
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone Mineral Density | First day of hospitalization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Brunnstrom | First day of hospitalization | — |
| Modified Barthel Index | First day of hospitalization | — |
| Modified Ashworth Scale | First day of hospitalization | — |
| Modified Fall Impact Scale | First day of hospitalization | — |
| Vitamin D, prealbumin, and albumin | First day of hospitalization | — |
| Baseline Digital Hand Dynamometer 198 LB/90 kg | First day of hospitalization | Patients' muscle strength will be measured using a Baseline Digital Hand Dynamometer at 198 LB/90 kg for both the dominant and non-dominant extremities. |
| Measurements of quadriceps muscle thickness and biceps muscle thickness | First day of hospitalization | Regional sarcopenia of the plegic and non-plegic extremities will also be assessed using the STAR formula with measurements of anterior thigh muscle thickness and anterior arm muscle thickness by ultrasound. |
Countries
Turkey (Türkiye)