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Assesment and Comparison of Osteoporosis Risk Factors After Stroke

Comparison of Osteoporosis Risk in the Subacute and Chronic Periods Following Stroke and Evaluation of Factors Increasing Osteoporosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07228611
Enrollment
84
Registered
2025-11-14
Start date
2025-12-05
Completion date
2026-05-01
Last updated
2026-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Osteoporosis

Brief summary

The aim of this study is to evaluate the effect of these factors and stroke itself on osteoporosis developing after stroke. Thus, the expected benefit of the study is to contribute to the identification and determination of the need for treatment in high-risk patients through further studies. There are no expected risks from the study.

Interventions

DIAGNOSTIC_TESTBone Mineral Density

Patients who have had a stroke and are at risk of fracture, and for whom routine assessment requires Bone Mineral Density (BMD) testing, will be included in the study. In addition, patients who have already undergone BMD testing for osteoporosis screening and who present to the outpatient clinic, with similar age and comorbidities, will be screened from the system, and 28 non-stroke patients who agree to participate will be included in the study.

Sponsors

Ankara Etlik City Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
55 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

1. Followed by ischemic or hemorrhagic stroke 2. Between 1 week and 6 months or \>1 year has passed since the date of the event 3. Being between 55 and 85 years of age

Exclusion criteria

1. The patient has additional neurological conditions besides stroke 2. The patient has a psychiatric condition 3. History of recurrent stroke 4. BMD scan performed within the last year for stroke patients 5. Having received osteoporosis treatment before or after the stroke 6. The patient having a fragility fracture before the stroke 7. The patient having a hip fracture or hip prosthesis 8. The patient having an additional condition that affects physical function before the stroke (amputation, severe fracture) 9. The patient has an additional disease or medication use that could cause secondary osteoporosis 10. The patient's stroke did not cause physical function loss

Design outcomes

Primary

MeasureTime frame
Bone Mineral DensityFirst day of hospitalization

Secondary

MeasureTime frameDescription
BrunnstromFirst day of hospitalization
Modified Barthel IndexFirst day of hospitalization
Modified Ashworth ScaleFirst day of hospitalization
Modified Fall Impact ScaleFirst day of hospitalization
Vitamin D, prealbumin, and albuminFirst day of hospitalization
Baseline Digital Hand Dynamometer 198 LB/90 kgFirst day of hospitalizationPatients' muscle strength will be measured using a Baseline Digital Hand Dynamometer at 198 LB/90 kg for both the dominant and non-dominant extremities.
Measurements of quadriceps muscle thickness and biceps muscle thicknessFirst day of hospitalizationRegional sarcopenia of the plegic and non-plegic extremities will also be assessed using the STAR formula with measurements of anterior thigh muscle thickness and anterior arm muscle thickness by ultrasound.

Countries

Turkey (Türkiye)

Contacts

CONTACTAyşe Naz Kalem Özgen, specialist
kalemnaz@gmail.com+90 0312 797 00 00

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026