Cerebral Oxygen Saturation
Conditions
Keywords
near infrared spectroscopy, coronary artery bypass grafting, regional cerebral oxygen saturation
Brief summary
The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO2) values measured on the monitor at twelve time points. The other primary outcome measures consist of baseline arterial and venous blood gas analysis and baseline activated clotting time measurements.
Detailed description
This prospective observational study analyzes 80 patients between the ages of 25-80 years who are undergoing elective coronary artery bypass grafting (CABG) surgery. Demographic data of the patients such as age, gender, comorbidities, body mass index are recorded. In addition to standard monitoring, cerebral oximetry monitoring (NIRS) is applied to the patients. Baseline arterial and venous blood gas analysis values, baseline activated clotting time measurements are recorded. Durations of anesthesia, surgery , cardiopulmonary bypass , aortic cross- clamping are recorded. Time points for rSO2 values are baseline, induction, sternotomy, cannulation, pump entry, cross clamp placement, 34º C ,36º C, lowest temperature, cross clamp removal, pump exit, skin closure.
Interventions
None listed
Sponsors
Tuna Şahin
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
25 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Accepting to participate in the study * Undergoing elective coronary artery bypass grafting surgery * Age 25-80 years Ejection fraction 30% and above
Exclusion criteria
* Non volunteers * Age \<25 or \>80 years * Ejection fraction below 30% * Patients with history of neurological disease or neurosurgery * Emergency surgery * Concurrent valve surgery * Patients with history of carotid artery stenosis * Patients with need for preoperative intraaortic balloon pump or inotropic support
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Regional oxygen saturation values | Baseline and peroperative measurements until the and of surgery | Regional oxygen saturation values measurement at twelve points. |
| Baseline arterial blood gas analysis | Within 5 minutes after arterial cannulation for the baseline measurement | The baseline arterial blood gas sample taken from the patient after arterial cannulation |
| Venous blood gas analysis | Within 5 minutes after central jugular venous cannulation | Venous blood gas sample taken from the patient after central jugular venous cannulation |
| Baseline activated clotting time measurement | Within 5 minutes after arterial cannulation for the baseline measurement | The baseline measurement of activated clotting time after arterial cannulation |
Countries
Turkey (Türkiye)
Outcome results
None listed