Alzheimer Dementia, Alzheimer Disease, Cognitive Abnormality, Delirium Confusional State, Encephalopathy
Conditions
Brief summary
The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such as delirium or encephalopathy), will result in an earlier diagnosis of underlying Alzheimer's disease. * Will this blood test have the ability to distinguish between Alzheimer's disease and other causes of cognitive impairment in the inpatient setting? * Neurology Clinic will complete a 6-month post-hospitalization follow up with patients who have had the Quest AD-Detect Alzheimer's Disease blood test completed while they were inpatient to discuss the risk assessment portfolio
Interventions
DIAGNOSTIC_TESTQuest AD-Detect blood test
Blood will be collected and sent for testing using the Quest AD-Detect blood test
Sponsors
Covenant Health, US
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Ages 60 to 90 years old * No prior diagnosis of dementia * Currently hospitalized with cognitive diagnosis, including but no limited to; delirium, encephalopathy, etc. thought to be secondary to a toxic/metabolic state
Exclusion criteria
* Age under 60 years * Prior diagnosis of dementing illness or other organic etiology to cognitive impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To show the percentage of patients (21 patients in the study) who presented with a cognitive diagnosis (including but not limited to delirium, encephalopathy, etc.) that have a positive biomarker for Alzheimer's dementia | From enrollment to 6 month follow up appointment with Neurology Clinic. | A Six month follow up with the Neurology clinic to discuss the results of Quest AD Detect (p-tau217), those patients who are found to have a positive outcome will receive additional follow-up in the Neurology clinic (which could include the use of additional lab tests or further diagnostic testing). |
Countries
United States
Contacts
Primary ContactClinical Research Nurse Coordinator
Outcome results
None listed