Exercise Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Conditions
Brief summary
The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).
Interventions
DIETARY_SUPPLEMENTLactobacillus casei
Probiohealth is the manufacturer of this strain and they use a stringent quality control program that utilizes a multi point product variability check system.
OTHERPlacebo Capsule(s)
The brand name of placebo capsules that will be used in this study is Magic Bullet Placebo Capsules. This placebo is manufactured by Progressive Placebo as stated on the product label.
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month * good general health with no injuries or health conditions that would affect physical activity * willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study
Exclusion criteria
* known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required * underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases * currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window * report using an NSAID more than twice a week on a regular basis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in perceived muscle soreness | From baseline to post 5-week intervention | Visual Analog Scale for perceived muscle soreness Each number on the scale will be designated with a descriptive word that corresponds to the soreness level they are experiencing. The scale will be laid out in order of increasing muscle soreness with "1" representing no pain. |
| Change in pressure pain threshold (PPT) | From baseline to post 5-week intervention | Calf pressure pain threshold (PPT) will be assessed by placing marks on the medial condyle of the femur and the posterior of the medial malleolus. The researcher will place the algometer on the muscle belly exactly halfway between the two marks. Volunteers will be instructed to specify when the first onset of pain occurs as the researcher gradually applies pressure. Quadricep measurements will involve the participant lying in the supine position where marks will be made on the anterior inferior iliac spine and the top of the patella so the researchers can once again find a point exactly halfway between these two locations to apply the algometer. Participants will be instructed to verbally indicate to the researcher when the onset of pain occurs as pressure is applied. |
| Change in countermovement jump assessment (CMJ) performance recovery | From baseline to post 5-week intervention | The researchers will demonstrate and instruct volunteers to "Stand upright with their hands above their head. When you are ready, bend your knees and stick your hips back while keeping your hands to your hips. Jump as high as possible and land softly." Participants will perform three CMJs separated by 60 seconds. Jump height will be recorded in cm and the highest value will be recorded. |
Countries
United States
Contacts
CONTACTJakob Fischer
PRINCIPAL_INVESTIGATORMary Stenson
University of Minnesota
Outcome results
None listed