Intent of Surgery for IPMN

Optimizing Preoperative Surgical Decision-making for Intraductal Papillary Mucinous Neoplasms: The Role of Intent of Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07216521

Enrollment

2000

Registered

2025-10-14

Start date

2025-09-15

Completion date

2025-12-31

Last updated

2025-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraductal Papillary Mucinous Neoplasm

Brief summary

This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion of IPMN-associated cancers diagnosed as overt pancreatic cancer with incidental IPMN association on pathology. 2. Compare clinicopathologic features and outcomes between surveillance-detected and incidentally detected IPMN-derived pancreatic cancers. 3. Revise and redefine risk features limited to patients undergoing surgery for IPMN-related indications, identifying optimal predictors of malignant IPMN (high-grade dysplasia or invasive cancer).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* All patients (18 years old of greater) who underwent surgical resection for IPMN (including low-, high-grade dysplasia, or invasive carcinoma) between July 1, 2015 and July 1, 2025.

Exclusion criteria

* Patients with concomitant pancreatic ductal adenocarcinoma (PDAC)

Design outcomes

Primary

Measure	Time frame
Grade of IPMN on Final Pathology	Day 0 (Retrospective Analysis)

Secondary

Measure	Time frame	Description
Recurrence Free Survival	Day 0 (Retrospective Analysis)	Length of time from surgery for IPMN to recurrence.
Overall Survival	Day 0 (Retrospective Analysis)	Length of time from surgery to death due to any cause.

Countries

China, Germany, Italy, Netherlands, United States

Contacts

Primary ContactCamila Hidalgo Salinas, MD

Camila.hidalgosalinas@nyulangone.org347-266-1376

Outcome results