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Knee Strengthening With Hip vs. Ankle Exercises in Women With Patellofemoral Pain Syndrome

Comparison of Knee Strengthening Combined With Hip or Ankle Joint Exercises on Clinical Symptoms, Sports Performance and Soft Tissue Structure in Women With Patellofemoral Pain Syndrome

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07210060
Enrollment
45
Registered
2025-10-07
Start date
2023-07-01
Completion date
2024-07-31
Last updated
2025-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral Pain Syndrome, Anterior Knee Pain, Exercise Therapy

Keywords

Dynamic alignment, Tele-rehabilitation, Pain modulation, Muscle strength

Brief summary

Eight weeks of telehealth-based supervised exercise effectively reduced DKV and pain in women with anterior knee pain. Both intervention groups demonstrated comparable benefits.

Detailed description

This study compared the effects of knee strengthening combined with either hip or ankle joint exercises on dynamic knee valgus (DKV), visual analogue scale (VAS) scores during activity, tendon stiffness, muscle structure, ankle range of motion, and muscle strength in women with anterior knee pain. Forty-five female recreational athletes aged 20-40 with anterior knee pain were randomly assigned to three groups: hip + knee exercises (HK group, n = 15), ankle + knee exercises (AK group, n = 15), and stretching alone (control group, n = 15). The HK and AK groups received supervised telehealth-based exercise sessions (30 minutes/day, 3 times/week for 8 weeks), while the control group received only an educational pamphlet. Assessments were conducted at baseline, 4 weeks, and 8 weeks.

Interventions

OTHERhip + knee joint exercise group

Hip: squat, glute bridge and gluteus medius exercise Knee: knee flexor and extensor, isometric squat hold

OTHERankle + knee joint exercise group

Knee: knee flexor and extensor, isometric squat hold Ankle: plantar flexor, dorsi flexor and lunge

Education Handout on Lower Limb Stretching

Sponsors

Kaohsiung Medical University Chung-Ho Memorial Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

1. Female recreational athletes aged 20-40 years who engage in regular exercise 2. Experiencing pain in the anterior or surrounding patella during at least two or more of the following activities: walking, running, jumping, kneeling, squatting, climbing stairs, or prolonged sitting 3. A pain index of 3 or higher on the Numeric Pain Rating Scale (NPRS) and symptoms persisting for at least 3 months 4. Knee pain unrelated to trauma.

Exclusion criteria

1. Inability to operate a smartphone or computer 2. History of fractures or surgeries involving the hip, knee, ankle, or foot 3. History of meniscus, knee ligament injuries, or ankle sprains within the last six months 4. Knee ligament laxity, inflammation, swelling, patellar dislocation, or subluxation 5. Cognitive impairment or inability to follow simple instructions 6. History of cardiovascular or neurological disorders 7. Advised by a physician to avoid exercise. Use of over-the-counter pain medication was not an exclusion criterion.

Design outcomes

Primary

MeasureTime frameDescription
Single Leg Landing Task2 minuteThe participant stood on a 30 cm box and first bent the non-testing leg's knee to approximately 90 degrees. After stabilizing, the participant jumped forward with the testing leg to a target 10 cm away from the box, maintaining balance for five seconds upon landing.

Secondary

MeasureTime frameDescription
Numeric Pain Rating Scale1 minute0 indicates no pain and 10 indicates the worst pain imaginable.
Patellar Tendon Stiffness Measurement3 minuteThe stiffness of the patellar tendon was assessed using a handheld device (MyotonPRO; Tallinn, Estonia).
Muscle structure15 minuteA portable ultrasound device (Linear wireless probe LU700L VET) was used to assess the structure of the gastrocnemius and gluteus medius muscles in a resting state.
Ankle Joint ROM3 minuteused a weight-bearing lunge test to measure the active dorsiflexion angle of the ankle during weight-bearing.
Maximum Voluntary Isometric Strength15 minuteA handheld dynamometer (MicroFET3; Hoggan Scientific LLC, USA) was used to measure the maximum isometric strength of the hip abductors, knee extensors, ankle dorsiflexors, and ankle plantar flexors.

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026