Antibiotic Prophylaxis, BPH With Urinary Obstruction
Conditions
Keywords
bph, urinary retention, antibiotic prophylaxis
Brief summary
To compare the risk of infectious complications (UTI, pyelonephritis, sepsis, hospital admission, ED visits) for patients with an indwelling urinary catheter (urethral or suprapubic) or CIC receiving 3 or 7 days of peri-operative antibiotic prophylaxis at time of Holmium Laser Enucleation of the Prostate
Interventions
DRUGantibiotic prophylaxis
we will compare varying durations of antibiotic prophylaxis prior to prostate enucleation surgery
Sponsors
Ohio State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Patients who are eligible to undergo HoLEP and have an indwelling urinary catheter or perform CIC will be randomized to different durations of peri-operative antibiotic prophylaxis
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 1\. Candidate for HoLEP surgery 2. Must be 18 years or older. 3. The patient must be able to understand and willing to provide informed consent as described in this study protocol.
Exclusion criteria
* 1\. Under the age of 18 2. Refuse to provide informed consent 3. Anticipated need for perineal urethrostomy 4. History of multi-drug resistant organism on urine culture that is not susceptible to any oral agents
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Infectious complications | 0-90 days postoperatively | UTI, pyelonephritis, sepsis, hospital admission, ED visits |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| healthcare utilization | 0-90days | hospital admission or ED visits occurring post HoLEP |
Contacts
Primary ContactMatthew Lee, MD
Outcome results
None listed