Cohort Study, Natural Population, Northwest Region of China
Conditions
Brief summary
This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.
Detailed description
This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health. The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.
Interventions
None listed
Sponsors
People's Hospital of Hotan Prefecture
People's Hospital of Altay Prefecture
Luopu County People's Hospital of Hotan Prefecture
The First People's Hospital of Aksu Prefecture
Karamay Central Hospital of Xinjiang
People's Hospital of Kizilsu Kyrgyz Autonomous Prefecture
The Second People's Hospital of Kashgar Prefecture
RenJi Hospital
People's Hospital of Xinjiang Uygur Autonomous Region
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Residents \>=18y 2. Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance 3. Residents without severe physical disability and capable of normal communication 4. Residents whose diseases and deaths are monitored and managed by the local health authorities 5. Residents who voluntarily participate and provide written informed consent
Exclusion criteria
1. Temporary residents or floating population 2. Residents with severe health conditions that prevent participation in the study 3. Residents who are unwilling to undergo follow-up assessments for the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Psychiatric diseases | 20 years | Incident disease during follow-up |
| Respiratory diseases | 20 years | Incident disease during follow-up |
| Ocular diseases | 20 years | Incident disease during follow-up |
| Dermatological diseases | 20 years | Incident disease during follow-up |
| Ear and mastoid disorders | 20 years | Incident disease during follow-up |
| Haematological or immunological diseases | 20 years | Incident disease during follow-up |
| Musculoskeletal diseases | 20 years | Incident disease during follow-up |
| Neurological diseases | 20 years | Incident disease during follow-up |
| Mortality | 20 years | All-cause and cause-specific mortality during follow-up |
| Cardiovascular diseases | 20 years | Incident disease during follow-up |
| Digestive diseases | 20 years | Incident disease during follow-up |
| Endocrine diseases | 20 years | Incident disease during follow-up |
| Infections diseases | 20 years | Incident disease during follow-up |
| Benign neoplasm or Carcinoma in situ | 20 years | Incident disease during follow-up |
| Cancers | 20 years | Incident disease during follow-up |
| Genitourinary diseases | 20 years | Incident disease during follow-up |
Countries
China
Contacts
Primary ContactQian Zhao, Dr.
Outcome results
None listed