Dengue Vaccination Strategy Evaluation, Public Health Impact of Vaccination, Transmission Modeling of Dengue
Conditions
Brief summary
This study is a collaboration between the School of Public Health at Fudan University and the Xishuangbanna Center for Disease Control and Prevention in Yunnan Province, China. It aims to evaluate the public health impact of dengue vaccination strategies using dynamic transmission models. By simulating different vaccination scenarios, the study will assess the potential effectiveness and public health benefits of dengue vaccine introduction, providing scientific evidence to support local dengue prevention and control efforts.
Interventions
None listed
Sponsors
Fudan University
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
3 Years to No maximum
Inclusion criteria
* Resident of Jinghong City, Xishuangbanna Prefecture * Aged 3 years and above * Able and willing to provide informed consent (or have legal guardian consent for minors) * Available for blood sample collection between May and August 2025
Exclusion criteria
* Individuals with bleeding disorders or other contraindications to blood draw * Individuals currently diagnosed with acute dengue infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dengue Virus Serological Response (IgM and IgG Antibody Levels) | From blood sample collection to the completion of laboratory analysis of dengue serology, serotype identification, and whole genome sequencing, from May to August 2025 |
Countries
China
Outcome results
None listed