Neovascular Glaucoma
Conditions
Keywords
Neovascular glaucoma, Retinal Vein Occlusion, Diabetic Retinopathy, Treatment
Brief summary
To explore the efficacy and safety of minimally invasive suprachoroidal drainage for the treatment of advanced neovascular glaucoma
Detailed description
To explore the efficacy and safety of minimally invasive supraporcular drainage in the treatment of advanced neovascular glaucoma, and to record the various basic diseases, ocular conditions, lifestyle, inflammatory markers and other parameters of NVG patients. To compare the safety and efficacy of new surgical methods and traditional surgical methods in order to find an effective treatment for neovascular glaucoma
Interventions
PROCEDUREminimally invasive suprachoroidal drainage
minimally invasive suprachoroidal drainage
Sponsors
Zhongnan Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Advanced (angle-closure) neovascular glaucoma with poorly controlled intraocular pressure (IOP \> 21mmHg) after medical or surgical treatment
Exclusion criteria
* Various other types of glaucoma (including primary open-angle glaucoma, primary open-closed glaucoma, normal tension glaucoma, juvenile glaucoma, congenital glaucoma, other special types of glaucoma, etc.) * Eye infection within two weeks before surgery * Non-glaucomatous intraocular diseases that affect intraocular pressure (choroidal hemorrhage or detachment, retinal detachment, lens subluxation, thyroid eye disease, clinically significant macular edema, eye tumors, etc.) * Visual acuity of non-study eyes \< 0.05 * Congenital or acquired factors lead to ciliary body anatomical abnormalities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ocular biological parameters | 1 day, 1 week, 1 month, 3 months, and 6 months after surgery | intraocular pressure |
| Surgical outcome measures | 1 day, 1 week, 1 month, 3 months, and 6 months after surgery | use of intraocular pressure lowering drugs |
| The success rate of surgery was evaluated according to the specific value of intraocular pressure after surgery | 1 day, 1 week, 1 month, 3 months, and 6 months after surgery | Complete success was defined as IOP within the normal range with no drug dependence, conditional success was defined as IOP within the normal range with drug dependence, and failure was defined as the rest |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The effective rate of surgery was evaluated according to the amplitude of IOP reduction after surgery and the change in the number of IOP-lowering drugs | 1 day, 1 week, 1 month, 3 months, and 6 months after surgery | Amplitude of IOP reduction: IOP change/initial IOP.The total number of IOP lowering drugs was recorded based on the number of active ingredients |
| Surgical outcome measures | 1 day, 1 week, 1 month, 3 months, and 6 months after surgery | complications |
Countries
China
Outcome results
None listed