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Does Psychotherapy Change the Gut Microbiome in Women of Child-bearing Age?

Impact of Biopsychosocial Psychotherapy Intervention on Maternal Life-Course Trauma and the Gut Microbiome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07200531
Enrollment
30
Registered
2025-10-01
Start date
2025-12-01
Completion date
2026-07-01
Last updated
2026-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Stress

Keywords

Gut Microbiome, Life-course trauma, Psychotherapy

Brief summary

The goal of this clinical trial is to learn if group therapy for six weeks changes the gut microbiome in women. The main questions it aims to answer are: Is chronic stress associated with the gut microbiome? Will six weeks of therapy change the gut microbiota? Participants will: Answer questionnaires about chronic stress Mail a stool sample before and after the intervention. Participate in a 1-hour group therapy session over the course of six weeks.

Interventions

BEHAVIORALPsychotherapy

6-week psychotherapy group intervention

Sponsors

University of Nebraska
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
19 Years to 54 Years
Healthy volunteers
Yes

Inclusion criteria

* Women over the age of 19 and less than 54. Able to understand/read English

Exclusion criteria

* Pregnant women and breast-feeding women Women who are actively participating in psychotherapy on a regular basis

Design outcomes

Primary

MeasureTime frameDescription
Depression, Anxiety, and Stress Scales6 weeksSelf-report mood disorder questionnaire
Perceived Stress6 weeksself-report questionnaire of perceived stress

Countries

United States

Contacts

CONTACTAshley J Blount, PhD
ablount@unomaha.edu4025596613
CONTACTTiffany A Moore, PhD, RN
tamoore@unmc.edu4025596613
PRINCIPAL_INVESTIGATORAshley J Blount, PhD

University of Nebraska

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026