Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
Conditions
Brief summary
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine.
Detailed description
Effective management of dental plaque is crucial for preventing periodontal diseases, dental caries, and other oral health complications. Oral hygiene can be maintained through both chemical and mechanical methods. Chemical methods are particularly beneficial in situations where mechanical cleaning proves challenging. Mouthwashes represent a significant chemical strategy for controlling plaque. Among different types of mouthwashes, chlorhexidine is considered the gold standard due to its high efficacy against a broad spectrum of bacteria and its role in plaque management, which helps prevent periodontal diseases. However, it is important to note that chlorhexidine has several side effects, such as numbness, changes in taste perception, dental staining, and an unpleasant bitter taste. In modern applications, nanotechnology is being utilized more frequently, especially with the integration of nanoparticle materials. Silver nanoparticles, in particular, are widely used in the medical field because of their remarkable antibacterial effects on oral biofilms associated with periodontal disease. Therefore, this research aims to evaluate the children's acceptance of chlorhexidine mouthwash in children compared to a mouthwash containing silver nanoparticles, as well as to assess their respective impacts on gingivitis.
Interventions
OTHERnano silver mouthwash
nano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients
the concentration of chlorhexidine
chlorhexidine mouthwash 0.2% (orovex )
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Intervention model description
randomized clinical trail on three groups
Eligibility
Sex/Gender
ALL
Age
6 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* Children aged from 6 to 12 in good general health and medically free * Cooperative patient who will care about attending the follow-up visit * Acceptance of the parents to sign the informed consent * Composite restoration on anterior teeth
Exclusion criteria
* Children who are unable to attend the follow-up visit * Medically compromised patient * Handi-capped patient * Parents refuse to sign informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| children acceptance and compliance | 15 days | it will be measured by likert scale (1-5) 1 (strongly disagree) 5 (strongly agree) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Gingival health | 15 days | \* gingival inflammation measured by modified gingival index scoring criteria (0-4) 0 (Normal gingiva ) 4 (sever inflammation of gingiva) |
| plaque thickness at gingival margin | 15 days | \* measure plaque thickness at gingival margin by plaque index by loe and silness scoring criteria (0-3) 0 (no plaque) 3 (thick plaque) |
| color stability of composite restoration of anterior teeth | 15 days | measure color stability of composite restoration of anterior teeth ΔE\* = √((L₂ - L₁)² + (a₂ - a₁)² + (b₂ - b₁)² Where: L\* = Lightness (0 = black, 100 = white) 1. = Red-Green axis (positive = red, negative = green) 2. = Yellow-Blue axis (positive = yellow, negative = blue * L1, a1, b1 = before exposure * L2, a2, b2 = after exposure A higher ∆E means more discoloration. |
Contacts
Primary ContactIbrahem mohamed Arafat
Outcome results
None listed