Perfusion Index and End Diastolic Velocity Ratios as Predictors of Supraclavicular Block Success in Vascular Access Surgery

Correlation Between Perfusion Index Ratio and End Diastolic Velocity Ratio After Supraclavicular Brachial Plexus Block as an Early Predictor of Successful Block in Superficialization Surgery of the Upper Limb

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07197281

Enrollment

Registered

2025-09-29

Start date

2026-05-01

Completion date

2027-12-30

Last updated

2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Diastolic Velocity, Perfusion Index

Keywords

End Diastolic Velocity, brachial plexus block, Perfusion Index

Brief summary

This is a prospective observational study investigating the correlation between Perfusion Index (PI) ratio and End Diastolic Velocity (EDV) ratio as early predictors of successful supraclavicular brachial plexus block (SCBPB) in patients undergoing superficialization surgery of the upper limb.

Detailed description

Regional anesthesia is fundamental for upper limb surgeries, with SCBPB providing dense anesthesia. However, early confirmation of successful block performance remains challenging. Traditional clinical methods (sensory/motor testing) are subjective and delayed. This study proposes using objective, noninvasive indices - PI (evaluated via pulse oximetry) and EDV (measured by Doppler ultrasound) - to determine their accuracy in detecting sympathetic blockade shortly after SCBPB. Early and reliable detection of block success is particularly important in superficialization surgeries such as arteriovenous fistula (AVF) superficialization in patients with compromised vascular status. The results are expected to enhance anesthesia practice by providing quantitative, reproducible, and rapid assessment tools.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Adults aged 18-65 years Both genders ASA II-VI classification Undergoing elective upper limb superficialization surgery (e.g., AVF superficialization) Provided written informed consent

Exclusion criteria

* Patient refusal Coagulopathy or bleeding disorders Local infection at injection site Allergy to local anesthetics Use of vasopressors or beta-blockers Severe peripheral vascular disease Morbid obesity (BMI \> 35) Severe neurological or psychiatric disorders

Design outcomes

Primary

Measure	Time frame	Description
Change in Perfusion Index ratio	15 minutes	Change in Perfusion Index ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block
Change in End Diastolic Velocity ratio	15 minutes	Change in End Diastolic Velocity ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block

Outcome results