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Hospital- and Home-Based Structured Pulmonary Rehabilitation in Recently Admitted COPD Patients: A Quasi-Experimental Study at Assiut University

Evaluation of Three Months Combined Hospital and Home-Based Tailored Rehabilitation Program in COPD Patients Recently Admitted to Chest Department of Assiut University Hospital

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07197229
Enrollment
70
Registered
2025-09-29
Start date
2026-04-30
Completion date
2027-12-30
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

COPD

Brief summary

This study evaluates the effect of a structured three-month pulmonary rehabilitation (PR) program, delivered both in-hospital and at home, on exercise capacity, respiratory symptoms, and functional status in stable COPD patients.

Detailed description

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity worldwide, significantly reducing patients' physical activity and quality of life. This study investigates a tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeks. The hospital component includes patient education, nutritional support, structured exercise training for both upper and lower limbs, and smoking cessation strategies. The home program emphasizes continuity with daily walking, strength exercises, and lifestyle modifications. The program aims to improve exercise capacity, dyspnea scores, and quality of life. Assessments include the six-minute walk test (6MWT), CAT score, mMRC dyspnea scale, spirometry, arterial blood gas analysis, and the St George's Respiratory Questionnaire. Measurements are collected at baseline and after program completion to assess improvements.

Interventions

BEHAVIORALPulmonary Rehabilitation

A tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeksParticipants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

ince this is a quasi-experimental single-arm study, there is only one intervention group the Pulmonary Rehabilitation Group: Participants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression).

Eligibility

Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Stable COPD patients diagnosed based on spirometry (post-bronchodilator FEV1/FVC \<70%) Age \> 40 years Moderate to severe COPD stage Able and willing to participate in rehabilitation program

Exclusion criteria

* Age \< 40 years Current acute COPD exacerbation at enrollment Significant comorbid conditions limiting participation (e.g., uncontrolled diabetes mellitus, uncontrolled hypertension, left-sided heart failure, renal failure, liver cell failure) Neuromuscular diseases, severe cognitive impairment, or psychiatric disturbance Pregnant patients Unwilling to participate in the rehabilitation program

Design outcomes

Primary

MeasureTime frameDescription
Six-Minute Walk Test (6MWT)12 weeksMeasures the distance (in meters) a patient can walk in six minutes as a marker of exercise capacity and functional endurance.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026