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Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods

Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods in Maxillary Incisors With Symptomatic Irreversible Pulpitis

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07196215
Enrollment
72
Registered
2025-09-29
Start date
2026-01-01
Completion date
2027-01-01
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Activation, Patient, Irrigation, Irriversible Pulpitis

Brief summary

root canal irrigation protocol

Detailed description

To compare mean post-operative pain intensity at different time intervals (24h and 48h) using visual analogue scale (VAS) in maxillary incisors with symptomatic irreversible pulpitis using two different irrigation activation methods (passive ultrasonic activation and sonic activation using EndoActivator).

Interventions

passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21/25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five

root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25/04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation

Sponsors

RANA AHMAD
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* • Patients in good health with no systemic disease (ASA Class I or II) * Age range is between 20 to 50 years. * Patients diagnosed with symptomatic irreversible pulpitis in maxillary incisor teeth. * Patients who can understand VAS. * Patients who give verbal consent to participate voluntarily in the study.

Exclusion criteria

* • History of systemic disorder. * Pregnant / lactating females (As per medical record/verbally) * Patients who had taken preoperative drugs as anti-inflammatory analgesic or antibiotics. * Patients with swelling or acute peri-apical abscess. * Tooth not suitable for restoration. * Periodontally compromised teeth. * Retreatment cases.

Design outcomes

Primary

MeasureTime frameDescription
pain score on visual analogue scale48 hoursAfter complete root canal irrigation and preparation, canals will be dried and a temporary dressing of Cavit will be placed. Patients will be reappointed for obturation. VAS scale ranging from 0-10 will be given to patient and will be demonstrated on how to record their pain and which will be recorded by the patient after 24 hours and 48 hours by marking on a chart ranging from 0-10 with 0 = no pain, 1-3 = mild pain, 4-6 = moderate pain 7-10 = severe pain. On 5th day of follow-up, obturation will be done using single cone obturation method

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026