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Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males

Both Acute Moderate-Intensity Continuous Exercise and High-Intensity Interval Exercise Increase Serum Oncostatin M Levels in Recreationally Active Males

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07195630
Enrollment
15
Registered
2025-09-26
Start date
2023-08-01
Completion date
2024-09-20
Last updated
2025-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males

Keywords

Acute Exercise, HIIT, Oncostatin M, MICE

Brief summary

The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally active, healthy men. Fifteen participants participated in both MICE and HIIE sessions. The HIIE session consisted of 10 x 1 min intervals at 90% of maximal oxygen uptake (VO2max) separated by a 75-second active recovery period at 60 W, whereas the MICE session consisted of a \ 21 min exercise session at 55% of VO2max. Blood samples were collected before (Pre) and immediately after (Post) acute MICE and HIIE sessions. Serum OSM levels were measured by the ELISA method.

Interventions

15 recreationally active males completed the \ 21 min of exercise at 55% of VO2max, consisting of a 3-minute warm-up and 3-minute cool-down at 60 W.

15 recreationally active males performed 10 x 1-minute intervals at 90% of VO2max, separated by 75 s of active recovery at 60 W, and a final 3-minute cool-down period at 60 W.

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Engaged in regular exercise/training in the last 6 months, * 18-30 years of age, * Body mass index (BMI) in the range of 18.5-24.9 kg/m².

Exclusion criteria

* Having a chronic disease that limits exercise, * Smoking, * Using any medication or supplement that may affect metabolism.

Design outcomes

Primary

MeasureTime frameDescription
Change from Pre- to Post-Exercise Levels of Oncostatin MFrom baseline assessment of blood samples at pre-exercise to the assessment of blood sample analysis at the end of the post-exercise.Serum samples were collected at pre- and post-exercise time points, and serum oncostatin M levels were measured using a commercial ELISA kit

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026