Multiple Sclerosis (MS), Periodontal Diseases
Conditions
Brief summary
The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population The main question it aims to answer is: • Is there an association between MS and periodontal disease Participants already diagnosed with multiple sclerosis. A conventional oral examination will be held on a dental unit, filling charts and patients' acceptance to participate in the survey.
Detailed description
Periodontal disease is a chronic inflammatory condition leading to progressive destruction of the supporting structures of the teeth. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that may share common inflammatory pathways with periodontal disease. Recent evidence suggests that systemic inflammation may influence the severity and progression of both conditions. This study will recruit participants already diagnosed with MS and assess their periodontal status using standard clinical parameters, including clinical attachment loss (CAL), probing pocket depth, and bleeding on probing measured at six sites per tooth using a periodontal probe. Data will be collected through a conventional oral examination in a dental unit, and results will be compared to evaluate the prevalence and potential association between MS and periodontal disease within this population.
Interventions
None listed
Sponsors
Cairo University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with MS * Adult patients ≥ 18 years old. * Patients providing an informed consent
Exclusion criteria
* Periodontal therapy within the last 3 months. * Having surgical therapy or undergoing orthodontic treatment * Smokers * Pregnant females * Patients with systemic condition know to impact the periodontal condition other than MS (eg. Diabetes Mellitus) * Patients having more than 5 lost teeth
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of periodontal disease as assessed by clinical periodontal parameters ( clinical attachment loss )within the study population. | Baseline | CAL will be measured as the distance from the cementoenamel junction (CEJ) to the base of the periodontal pocket using a periodontal probe at six sites per tooth. Mean CAL will be calculated for each participant to assess periodontal tissue destruction. |
Countries
Egypt
Outcome results
None listed