Sexual Dysfunction in Women With Multiple Sclerosis (MS)

Sexual Dysfunction Prevalence and Its Relationship With Various Factors in Women With Multiple Sclerosis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07193823

Acronym

Enrollment

140

Registered

2025-09-26

Start date

2024-07-16

Completion date

2025-11-30

Last updated

2025-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Cognitive Dysfunction, Depression, Fatigue, Fatigue in Multiple Sclerosis, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Overactive Bladder, Sexual Disfunction

Keywords

multiple sclerosis, sexual dysfunction, cognitive dysfunction, depression, anxiety, overactive bladder, fatigue

Brief summary

Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with MS. The secondary objective is to evaluate the relationship between sexual dysfunction and fatigue, depression, anxiety, overactive bladder symptoms, and cognitive dysfunction. For this purpose, the following validated instruments will be used: the Female Sexual Function Index (FSFI) to assess sexual dysfunction, the Brief International Cognitive Assessment for MS (BICAMS) to evaluate cognitive function, the Hospital Anxiety and Depression Scale (HADS) to assess depression and anxiety, the Fatigue Severity Scale (FSS) to measure fatigue, and the Overactive Bladder Questionnaire (OAB-V8) to evaluate overactive bladder symptoms.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Female patients aged 25-50 years * Literate and able to comprehend written and spoken instructions * Diagnosed with relapsing-remitting form of multiple sclerosis * Having a continuous/regular sexual partner * Expanded Disability Status Scale (EDSS) score ≤ 5 * At least 3 months since the last relapse * Sexually active within the past 3 months * Spasticity level \< grade 2 according to the Modified Ashworth Scale

Exclusion criteria

* Pregnancy * Illiteracy or inability to understand spoken or written instructions * Absence of a continuous/regular sexual partner * Expanded Disability Status Scale (EDSS) score \> 5 * Not sexually active within the past 3 months * Spasticity level ≥ grade 2 according to the Modified Ashworth Scale

Design outcomes

Primary

Measure	Time frame
Prevalence of sexual dysfunction in female patients with multiple sclerosis	At enrollment (Baseline, cross-sectional assessment)

Secondary

Measure	Time frame
Association between sexual dysfunction and cognitive dysfunction, fatigue, depression, anxiety, and overactive bladder symptoms	At enrollment (Baseline, cross-sectional assessment)

Countries

Turkey (Türkiye)

Contacts

Primary ContactMerve Dokumaci, Resident doctor

dokumacimerve@gmail.com+905435088428

Outcome results