Delirium, Post ICU Syndrome
Conditions
Keywords
ICU delirium, Phenotypes, Physical impairment, Cognitive impairment, Mental health impairment, ICU transition
Brief summary
The goal of this observational study is to learn about the disability profile during transition from ICU to hospital wards of delirium patients, including cognitive impairment, physical dysfunction and psychological disorders. The main question it aims to answer is: * What is the main rehabilitation problem during transition from ICU to hospital wards for patients who experienced ICU delirium? * Dose different phenotypes of ICU delirium shows different rehabilitation problem during ICU transition? Participants will be followed up and assessed by questionnaires after discharge from ICU to hospital wards until hospital discharge.
Interventions
OTHERPhenotypes of ICU delirium
The included delirium patients will be divided into different phenotypes, according to delirium risk factors such as age, history of cerebrovascular accident, blood transfusion, surgery duration etc.
Sponsors
National Natural Science Foundation of China
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* patients aged above 18-year-old * at least one positive screening of CAM-ICU (Confusion Assessment Method for ICU) assessment during ICU stay * patients are transferred to hospital ward after ICU discharge
Exclusion criteria
* patients are with severe dementia * blindness, deafness or inability to understand mandarin * life expectancy of less than 24h * stayed in ICU more than one-month after the first CAM-ICU positive screening
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physical impairment | At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge | The Modified Barthel Index is a widely used scale for assessing a patient's level of independence in activities of daily living (ADLs). Each activity is scored based on the degree of assistance required, with total scores typically ranging from 0 (complete dependence) to 100 (complete independence). |
| Cognitive impairment | At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge | The Mini-MoCA (Mini Montreal Cognitive Assessment) is a brief cognitive screening tool derived from the full MoCA, designed to rapidly assess cognitive function in clinical and hospital settings. It evaluates key domains such as orientation, attention, memory, language, and visuospatial skills, using a condensed format suitable for bedside. |
| Mental health | At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge | Hospital Anxiety and Depression Scale(HADS) is a 14-item tool used to screen for anxiety and depression in hospitalised patients. It includes two 7-item subscales, each scored 0-21, with higher scores indicate more severe psychological distress. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital stay | up to 30 days | Duration of hospital stay |
| In-hospital Mortality | up to 30 days | Mortality during hospital stay |
Countries
China
Contacts
Primary ContactShining CAI, PhD
Outcome results
None listed