Urine Specimen Collection
Conditions
Brief summary
To develop and validate a urine drug screen to detect thebaine.
Interventions
None listed
Sponsors
Children's Hospital Medical Center, Cincinnati
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female * Ages 18-65 * Healthy
Exclusion criteria
* Allergy to poppy seeds, or any of the related food stuffs used in the study * Celiac disease or gluten sensitivity * Ongoing or opioid use in the past 6 months * History of renal or hepatic disease or dysfunction * Inability or unwillingness to give repeated urine specimens * Unwillingness to refrain from eating poppy seed-containing products during the two-day course of the study * Non-English speakers (due to study materials being in English) * BMI greater than 30 * Antibiotic use in the previous 2 months * Recent ingestion of poppy seeds from the previous 7 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Validate thebaine urine screen | Enrollment to 48 hours after enrollment | Validate a liquid chromatography-tandem mass spectrometry method to detect thebaine in urine |
Countries
United States
Contacts
Primary ContactCharlotte Walter, MD
Outcome results
None listed