COVID - 19
Conditions
Keywords
Covid-19, olfactory training, olfactory and taste loss
Brief summary
The purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.
Detailed description
The purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.
Interventions
OTHEROlfactory rehabilitation consists of smelling a series of spices every day for 2 months
Olfactory rehabilitation consists of smelling a series of spices every day for 2 months: vanilla, coffee, dill, thyme, cinnamon, cloves, lavender, coriander, light vinegar, mint, and cumin. This rehabilitation is based on the protocols proposed by SFORL (French ORL society) and Oleszkiewicz et al.8 Allergies to certain spices will be noted at the start of the study: * in known allergy: change by another spice which belongs to the same chemical category. * in case of allergies to several scents: patient is not included in the study. * in case of allergy appearing during participation: clinical evaluation by ENT, change by another spice which belongs to the same chemical category. * in case of allergies to several scents occuring during participation: patient is excluded from the study.
Sponsors
Centre Hospitalier Universitaire de la Guadeloupe
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Caregiver)
Intervention model description
To prove this efficiency, a parallel prospective comparative study appear to be one of the best the way.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* SARS-CoV-2 infection suspect or confirmed * supported by CHU Guadeloupe * with brutal olfactory or taste loss * affiliated or beneficiary of a social security scheme * informed consent signed
Exclusion criteria
* recent rhinosinusitis, less than 6 months * lingual pathology * communication disorder * Patients subject to a justice safeguard * Allergy to several spices that are part of the rehabilitation set * Pregnant or breastfeeding women * Absence of signed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Taste and Smell Survey (TSS). | Baseline and 2 months | Patients will have this auto evaluation scale at the inclusion (D0) and 2 month after inclusion (D60). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sniffin' stick test : | 2 month | The Sniffin' Stick Test assesses the sense of smell by measuring odor detection threshold, discrimination, and identification, and is used for diagnosing and monitoring olfactory disorders. |
| Olfaction and taste evolution evaluated with a daily visual scale | Every day from inclusion to 2 months | Visual analogue scale from 0 to 10 to assess dysosmia and dysgeusia, with 0 indicating normal function and 10 indicating complete deficit. |
Countries
Guadeloupe
Outcome results
None listed