Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients

Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients: a Randomized Controlled Trial

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07188272

Enrollment

Registered

2025-09-23

Start date

2025-07-10

Completion date

2026-01-01

Last updated

2026-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arterial Stiffness, Hypertension

Brief summary

Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients

Interventions

DIETARY_SUPPLEMENTDASH diet

Eating vegetables, fruits, and whole grains Including fat-free or low-fat dairy products, fish, poultry, beans, nuts, and vegetable oils Limiting foods that are high in saturated fat, such as fatty meats, full-fat dairy products, and tropical oils such as coconut, palm kernel, and palm oils Limiting sugar-sweetened beverages and sweets

PROCEDUREHigh Intensity Interval Training

High Intensity Interval Training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

35 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Their age\< 35 up to 50 years old * Both sexes. * Controlled HTN ( stage 1,B.P 140-159 mmhg / 90-99 mmhg and stage 2, B.P 160-179 mmhg-100-109 mmhg ) * Hemodynamic stable. Able to provide informed consent

Exclusion criteria

* Uncontrolled hypertension. * Severe HTN \<180/110 mmhg * Renal dysfunction * Unstable cardiac conditions * Severe pulmonary disease that limit exercise * Impaired cognition * Musculoskeletal problems that made it difficult to do exercise

Design outcomes

Primary

Measure	Time frame	Description
Pulse Wave Velocity	each week	normal level 60-100 per minutes

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 4, 2026