Esophageal Cancer
Conditions
Brief summary
1. Research methods Constructed the "Manual for Graded Management of Postoperative Symptoms of Esophageal Cancer" and developed continuous care Procedures. 2. Randomised controlled studies were conducted to verify the effects of the procedure.
Interventions
DEVICESmart Symptom Management Program
During the first six months after surgery, patients in the experimental group will use a WeChat mini-program to proactively self-report their symptoms regularly using the Chinese version of the MD Anderson Symptom Inventory for Esophageal Cancer (MDASI-EC). Based on the reported scores and the pre-defined algorithms in the "Post-Esophagectomy Symptom Grading Management Manual", the system will automatically provide personalized self-management guidance for low-grade symptoms. For more severe symptoms, the system will generate alerts to prompt dedicated study nurses to initiate proactive telephone follow-up and provide tailored health coaching.
Sponsors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patient is aware and able to communicate in Mandarin; * There are smartphones； * Proficient in using WeChat mini programs. * Patients who were scheduled for esophageal cancer resection in participating centers were eligible for inclusion.
Exclusion criteria
* Have cognitive impairment or psychiatric illness; * Refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of the proportion of patients with any of three esophageal cancer-specific symptoms (reflux, dysphagia, eating difficulty) | 12 weeks after surgery | Primary outcome was the proportion of patients with any of three esophageal cancer-specific symptoms (reflux, dysphagia, eating difficulty) rated ≥4 on the MDASI-EC at 12 weeks after surgery. This composite endpoint was selected based on our prior symptom trajectory studies, as these three symptoms are the most common and most distressing after esophagectomy. |
Secondary
| Measure | Time frame |
|---|---|
| the proportion of patients with a score ≥4 for each individual symptom items | 12 weeks after surgery |
| composite functional interference scores: WAW (the average of walking, general activity, work) and REM (the average of relations with others, mood, enjoyment of life) | 12 weeks after surgery |
| 30-day unplanned hospital readmission rate (including emergency department visits or unscheduled outpatient visits). | 30 days after surgery |
Countries
China
Contacts
CONTACTYUAN YU
Outcome results
None listed