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Strength Training With and Without Blood Flow Restriction on Shoulder Muscle Strength in Healthy Adults

Comparative Effects of Blood Flow Restriction and Traditional Strength Training on Proximal Shoulder Musculature: A Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07186231
Enrollment
23
Registered
2025-09-22
Start date
2024-04-08
Completion date
2024-05-30
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Flow Restriction (BFR) Training Effects, Resistance Training

Keywords

Resistance training, Blood Flow Restriction, Hypertrophy, Strength, Power, Endurance

Brief summary

The goal of this clinical trial is to compare two types of shoulder strength training: low-load training with blood-flow restriction (BFR) and high-load training without BFR. The study includes healthy adults. The main questions it aims to answer are: Are changes in shoulder strength, power, endurance, and muscle mass similar with low-load BFR and high-load training? Researchers will compare strength training with BFR to strength training without BFR to see whether changes in shoulder muscle performance are similar. Participants will: * Provide basic personal details, body measurements (e.g., height and weight), and a brief medical history before starting. * Train in one of the two programs (BFR or no BFR) two times per week for 4 weeks. * Complete tests of shoulder maximum strength, power, endurance, and muscle mass at the start and at the end of the protocol.

Detailed description

All outcome assessments were conducted after a standardized warm-up to minimize measurement variability. The warm-up comprised light aerobic activity, followed by dynamic mobility exercises for the shoulder girdle and upper limbs, and targeted stretching of the shoulder and elbow/forearm muscle groups (two sets of 20-30 seconds per muscle group). Safety procedures included monitoring for adverse symptoms during testing and training; sessions were paused or discontinued according to predefined criteria.

Interventions

Each session began with a warm-up including mobility and stretching exercises for the shoulders and upper limbs. During the first session, the one-repetition maximum (1RM) for each participant and exercise was determined using a failure-to-repetition method with applied coefficients. Training was performed at 30 percent 1RM, following a standardized sequence of three shoulder-targeted exercises (shoulder abduction, external rotation, Dumbbell Overhead Press), totaling 75 repetition per session (30/15/15/15), 30-second rest intervals per sets. Movements were executed at a controlled 4-sec. tempo (2 seconds concentric, 2 seconds eccentric). BFR was applied using pneumatic cuffs, maintained during each exercise, released for 60 seconds between exercises, and reapplied for the next. Participants rated exercise difficulty, including pain, tension, and numbness, using a 0-10 numeric scale, with protocol adjustments or session cancellation if symptoms exceeded 7/10.

OTHERHigh-load resistance training.

Each session began with a warm-up including mobility and stretching exercises for the shoulders and upper limbs. During the first session, the 1RM for each participant and exercise was determined using a failure-to-repetition method with applied coefficients. Training was performed at 70 percent following a standardized sequence of three shoulder-targeted exercises (shoulder abduction and external rotation, and Dumbbell Overhead Press). Four sets of 8 to 10 repetitions were completed for each exercise, with 2-minutes rest between sets and exercises. Movement speed was moderate (1-second concentric, 2-second eccentric).

Sponsors

Alice Maria da Costa Carvalhais
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Body Mass Index between 18.5 and 30 kg/m²

Exclusion criteria

* participation in sports that heavily involve the dominant arm (e.g., tennis, volleyball, or handball) and do not engage in strength training exercises on the upper limb; * history of trauma or surgery affecting the dominant upper limb; * acute or chronic shoulder pain,; * radiating pain; * cervical disc herniation; * previous neck surgeries,; * upper limb edema; * history of deep vein thrombosis; * history of oncologic or metabolic conditions; * pregnancy; * experience of persistent symptoms such as numbness, tingling, or pain exceeding 7/10 on a numeric scale during the training (applicable to BFR group); * missed more than one session during the study.

Design outcomes

Primary

MeasureTime frameDescription
Change in Deltoid muscle massBaseline and between 24 hours and 1 week after completion of the 4-week intervention.Arm circumference at the armpit level of the dominant limb, used as a proxy for deltoid muscle mass.
Change in shoulder muscle powerBaseline and between 24 hours and 1 week after completion of the 4-week intervention.Shoulder muscle power, assessed by the Single Arm Seated Shot-Put Test
Change in shoulder muscle maximal strengthBaseline and between 24 hours and 1 week after completion of the 4-week intervention.Maximal isometric muscle strength measured with the Smart Groin Trainer dynamometer (NeuroExcellence, Braga, Portugal) during a vertical lift task.
Change in muscle shoulder enduranceBaseline and between 24 hours and 1 week after completion of the 4-week intervention.Shoulder muscle endurance, assessed by the Shoulder Endurance Test (SET)

Secondary

MeasureTime frameDescription
Change in Numeric Rating ScaleContinuously from the start to the end of each training session, across all sessions during the 4-week intervention (participants report immediately if symptoms reaches ≥7/10.Participants in the Low-load strength training with BFR group rate pain, numbness and tingling in the dominant upper limb on a 0-10 Numeric Rating Scale (NRS) (0 = none; 10 = worst imaginable). Sessions are paused if NRS ≥ 7/10.

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026