Stress Urinary Incontinence, Ultrasound, Vascularisation, Urodynamic Exam
Conditions
Brief summary
The urethra plays a crucial role in maintaining urinary continence. Its complex blood supply is still not well understood. Particularly in the context of urethral pressure. Urethral pressure can be measured by bladder and urethral pressure studies (urodynamic). This study aims to use advanced imaging techniques to analyse the blood supply of the urethra and correlate it to urethral pressure measurements. Elucidating these relationships will improve our understanding of urethral function and malfunction, and ultimately optimise diagnosis and treatment of stress urinary incontinence. A total of 35 participants with stress urinary incontinence and 35 without stress urinary incontinence will be asked to participate in this study.
Interventions
DIAGNOSTIC_TEST3D Ultrasound
Virtual Organ Computer-aided AnaLysis (VOCAL) to assess flow and velocity characteristics of the urethral blood supply
Sponsors
Insel Gruppe AG, University Hospital Bern
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Urodynamic examination * Written informed consent * Understanding of the German language * Indicated urodynamic assessment * Endovaginal and perineal ultrasound feasible
Exclusion criteria
* Urinary tract infections * Transgender Population * Pregnancy * History of incontinence or prolapse surgery * Pelvic prolapse higher than second degree * Prior pelvic radiotherapy * Prior history of gynecologic tumor
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Color histogram index (Vascularity Index) | Enrollment by the urodynamic examination until the ultrasound measurement (VOCAL) up to 4 weeks | Doppler Indices (Vascularity Index) generated by Virtual Organ Computer-aided AnaLysis (VOCAL) |
Countries
Switzerland
Outcome results
None listed